Patient Perspectives on Triggers, Adherence to Medical Recommendations, and Disease Control in Atopic Dermatitis: The DATOP Study

Frutos, F.J. Ortiz de; Torrelo, Antonio; Lucas, R. de; Gonzalez, MI; Alomar, A.; Vera, Ángel Jacinto Traver; Ros, S.; Mora, A.; Cuervo, Jesús

doi:10.1016/j.adengl.2014.04.012

Cited by 17 publications

(22 citation statements)

References 30 publications

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“…In this nationwide registry‐based study, lower temperature correlated best with increased healthcare utilization and ostensibly flares among AD patients. While this, in general, conforms to previous studies, this is the largest study to date encompassing more than 50 000 visits and 1 000 000 TCS and TCI prescriptions. Specifically, there were ~264 more TCI and ~90 more TCS prescriptions filled per month by AD patients for every 5°C drop in temperature.…”

Section: Discussionsupporting

confidence: 91%

The effects of season and weather on healthcare utilization among patients with atopic dermatitis

Hamann

Andersen

Engebretsen

et al. 2018

Acad Dermatol Venereol

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Section: Discussionsupporting

confidence: 91%

The effects of season and weather on healthcare utilization among patients with atopic dermatitis

Hamann

Andersen

Engebretsen

et al. 2018

Acad Dermatol Venereol

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“…87 Sudden changes in temperatures may also be perceived as a possible trigger for AD exacerbation. 88 In another study, the only significant association between environmental factors and flare of disease was damp weather. 89 A recent study also suggested a connection between loss-offunction mutations in the FLG and the susceptibility to climatic exposure in patients with AD.…”

Section: Atopic Dermatitismentioning

confidence: 95%

“…In school children with AD, 40% felt that hot weather worsened their symptoms, whereas 28% felt that cold weather worsened their disease . Sudden changes in temperatures may also be perceived as a possible trigger for AD exacerbation . In another study, the only significant association between environmental factors and flare of disease was damp weather …”

Section: Effect Of Seasonal and Climatic Variations On The Risk Of Dementioning

confidence: 96%

The effect of environmental humidity and temperature on skin barrier function and dermatitis

Engebretsen

Johansen

Kežić

et al. 2015

Acad Dermatol Venereol

227

162

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Physicians are aware that climatic conditions negatively affect the skin. In particular, people living in equator far countries such as the Northern parts of Europe and North America are exposed to harsh weather during the winter and may experience dry and itchy skin, or deterioration of already existing dermatoses. We searched the literature for studies that evaluated the mechanisms behind this phenomenon. Commonly used meteorological terms such as absolute humidity, relative humidity and dew point are explained. Furthermore, we review the negative effect of low humidity, low temperatures and different seasons on the skin barrier and on the risk of dermatitis. We conclude that low humidity and low temperatures lead to a general decrease in skin barrier function and increased susceptible towards mechanical stress. Since pro-inflammatory cytokines and cortisol are released by keratinocytes, and the number of dermal mast cells increases, the skin also becomes more reactive towards skin irritants and allergens. Collectively, published data show that cold and dry weather increase the prevalence and risk of flares in patients with atopic dermatitis.

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“…Multiple possible reasons for this have been advocated, including diet, stress, heat, sweating, damp, and external irritants. Pollen exposure and air pollutants are also factors that have been implicated . Warmer temperatures can result in earlier and higher intensity of pollen, thereby triggering an eczema flare .…”

Section: How Climate Change May Affect Atopic Dermatitismentioning

confidence: 99%

Climate change and atopic dermatitis: is there a link?

2018

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Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease with a growing health concern, because of its high prevalence and associated low quality of life. The etiology of AD is multifactorial with interaction between various factors such as genetic predisposition, immune, and importantly, environmental factors. Since climate change is associated with a profound shift in environmental factors, we suggest that AD is being influenced by climate change. This review highlights the effects of ultraviolet light, temperature, humidity, pollens, air pollutants, and their interaction between them contributing to the epidemiology and pathophysiology of AD.

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Patient Perspectives on Triggers, Adherence to Medical Recommendations, and Disease Control in Atopic Dermatitis: The DATOP Study

Cited by 17 publications

References 30 publications

The effects of season and weather on healthcare utilization among patients with atopic dermatitis

The effects of season and weather on healthcare utilization among patients with atopic dermatitis

The effect of environmental humidity and temperature on skin barrier function and dermatitis

Climate change and atopic dermatitis: is there a link?

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