Patient‐perceived severity of synkinesis reduces quality of life in facial palsy: A cross‐sectional analysis in 92 patients

Veen, Martinus M. van; Quatela, Olivia; Tavares-Brito, Joana; Robinson, Mara; Baiungo, Jennifer; Werker, Paul M. N.; Dijkstra, Pieter U.; Hadlock, Tessa A.

doi:10.1111/coa.13322

Cited by 27 publications

(22 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to the present study, most publications on series of PFS patients report of a weak to moderate predominance of women of between 55% and 75% 28,29 . Women seem not to be more vulnerable for the development of PFS but suffer more from PFS than men 30,31 . They might, therefore, look for help more frequently and may be overrepresented in PFS studies.…”

Section: Discussionsupporting

confidence: 86%

Role of Body Dysmorphic Disorder in Patients With Postparalytic Facial Synkinesis

et al. 2021

View full text Add to dashboard Cite

Objectives/Hypothesis To evaluate the role of body dysmorphic disorder (BDD) in patients with postparalytic facial nerve syndrome with synkinesis (PFS). Study Design A single‐center retrospective cohort study. Methods A total of 221 adults (74% women; median age: 44 years; median duration since onset of facial palsy: 1.6 years) were included. To diagnose BDD, the BDD Munich Module was used. Associations with House‐Brackmann grading, Stennert index grading, Facial Clinimetric Evaluation (FaCE) survey, Facial Disability Index (FDI), general quality of life (SF‐36), Beck Depression Inventory (BDI), and the Liebowitz Social Anxiety Scale (LSAS) was analyzed. Results A total of 59 patients (27%) were classified as patients with BDD. Significant associations were found between the diagnosis of BDD and female gender and lower FDI, FaCE, and SF‐36 scores and higher BDI and LSAS scores. Multivariate analysis revealed BDI, FaCE total score, and FaCE social function subscore as independent factors associated with BDD. Conclusion BDD was a relevant diagnosis in patients with PFS. A higher BDD level was associated with general and facial‐specific quality of life and more psychosocial disabilities. Optimal treatment of PFS has to include these nonmotor dysfunctions. Level of Evidence 3 Laryngoscope, 131:E2518–E2524, 2021

show abstract

Section: Discussionsupporting

confidence: 86%

Role of Body Dysmorphic Disorder in Patients With Postparalytic Facial Synkinesis

et al. 2021

View full text Add to dashboard Cite

show abstract

“…For synkinesis, this result is statistically significant given the impact on quality of life. 37 However, very few evaluations of syncinesis are reported in the literature for reconstruction by vascularized nerve grafting, which makes it difficult to compare our results. 11,14,17,22,23,[30][31][32][33][34] About Frey's syndrome, we noted the absence of clinical Frey syndrome, and Frey syndrome complains in our cohort.…”

Section: Discussionmentioning

confidence: 96%

Facial functional outcomes analysis after reconstruction by vascularized thoracodorsal nerve free flap following radical parotidectomy with facial nerve sacrifice

et al. 2020

View full text Add to dashboard Cite

show abstract

“…We believe this means the experienced burden of synkinesis is much more individual compared to flaccid paralysis, as is supported by a previous study demonstrating the importance of incorporating patient selfexperience synkinesis scores in QoL modelling in patients suffering from synkinesis. 9 One of the limitations of our study was that we reanalyzed data previously collected in two different centres. All Sunnybrook scores were performed by experienced assessors.…”

Section: Discussionmentioning

confidence: 99%

A cross‐sectional analysis of facial palsy‐related quality of life in 125 patients: Comparing linear, quadratic and cubic regression analyses

Verhoeff

Bruins

Ingels

et al. 2022

Clinical Otolaryngology

Self Cite

View full text Add to dashboard Cite

Introduction Facial function correlates with quality of life in facial palsy. Previous studies have examined a linear relationship; based on clinical experience, we hypothesize a curved regression (i.e. quadratic or cubic) will be more fitting to show the correlation between quality of life and facial function. Methods We compared the fit of a linear regression model between Sunnybrook scores (facial function) and FaCE and FDI scores (quality of life) to a quadratic and cubic regression model in 125 patients cross‐sectionally. Results A total of 125 patients were included, 53.6% female with a mean (standard deviation) age of 56.6 (16.7) and a median (interquartile range) duration of palsy of 6.6 (1.5; 18.3) years. The quadratic regression proved a significant improvement over a linear regression analysis in the model using the FaCE total score (linear R2 =.346, quadratic R2 = .378, p = .033) and the FDI physical score (linear R2 = .245, quadratic R2 =.276, p = .034). The cubic regression analysis was no significant improvement over a quadratic regression. Discussion The relationship between facial function and quality of life in facial palsy is not linear meaning that there is a lot of variation in QoL in cases with severe and moderate facial impairment. This is most applicable to patients suffering from post‐paralysis synkinesis, proving the highly individually experienced burden of synkinesis. As the relationship is not linear it should not be included as such in future research studies.

show abstract

Patient‐perceived severity of synkinesis reduces quality of life in facial palsy: A cross‐sectional analysis in 92 patients

Cited by 27 publications

References 12 publications

Role of Body Dysmorphic Disorder in Patients With Postparalytic Facial Synkinesis

Role of Body Dysmorphic Disorder in Patients With Postparalytic Facial Synkinesis

Facial functional outcomes analysis after reconstruction by vascularized thoracodorsal nerve free flap following radical parotidectomy with facial nerve sacrifice

A cross‐sectional analysis of facial palsy‐related quality of life in 125 patients: Comparing linear, quadratic and cubic regression analyses

Contact Info

Product

Resources

About