Patient Outcomes Following Micropulse Transscleral Cyclophotocoagulation: Intermediate-term Results

Yelenskiy, Aleksandr; Gillette, Thomas B.; Arosemena, Analisa; Stern, Augustus G; Garris, Winston J; Young, Curt T; Hoyt, Michelle; Worley, N. Knight; Zurakowski, David; Ayyala, Ramesh S.

doi:10.1097/ijg.0000000000001023

Cited by 77 publications

(79 citation statements)

References 24 publications

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“…Pak J Ophthalmol delivers continuous, high intensity energy, MP3 delivers repetitive short pulse laser energy series followed by rest period 8,15,[16][17][18] . Complications related to cyclodestruction procedure includes vision loss, pupillary distortion, corneal edema, cystoid macula, hypotony, and edema 19,20 .…”

Section: Resultsmentioning

confidence: 99%

“…Yelenskiy A reported 71% effectivness. 19 Success rate varies from 40% to 80% in different studies [22][23][24] .…”

Section: Resultsmentioning

confidence: 99%

“…The limitation of our study is the short-term follow up but we are continuing our study for long term follow-up. Previously, cyclodestructive procedures such as cyclocryotherapy and CPC were reserved for poorly controlled glaucoma, limited visual prognosis and mainly retained for end stage glaucoma, because of associated complication with cyclodestructive procedures that include vision loss, corneal edema, pupillary distortion, cystoid macula edema, and hypotony 19 . We did not notice any significant complications following MP-TSCPC in our study.…”

Section: Resultsmentioning

confidence: 99%

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Effectiveness of Micropulse MP3 Cyclodiode Laser in controlling Intraocular pressure without Acetazolamide

et al. 2020

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ABSTRACT Background: Glaucoma is a 2ndleading cause of irreversible blindness worldwide. Primary surgical procedures include trabeculectomy with or without anti-metabolites, as well as glaucoma drainage devices. Cycloablation lowers IOP by destruction of ciliary body epithelium and stroma, thus reducing aqueous production. Objective: To determine effectiveness of micropulse mp3 cyclodiode laser in controlling intraocular pressure without acetazolamide. Study design: Descriptive case series study Place and duration of study: Department of Ophthalmology, Liaquat National Hospital, Karachi for 6 months duration Material and Methods: In our study total 98 patients of either gender with age 20 to 50 years, following inclusion criteria (Chronic open angle glaucoma, Neovascular, Refractory, Uveitic, Trauma induced glaucoma, and Post vitrectomy induced glaucoma) and exclusion criteria (Primary angle closure and Normal tension glaucoma) were included. Descriptive statistics were calculated. Frequencies and percentages were computed for qualitative variables. Quantitative variables were presented as mean±standard deviation. The mean baseline IOP was compared with mean IOP of 3 months using student t-test. Effect modifiers were controlled through stratification. Fisher exact test was used to see the association of effectiveness with stratified groups. P-value ≤0.05 was considered as significant. Results: Among total 98 patients, 63.3% were male and 36.7% were female. Mean age was 48.46±13.39 years. The effectiveness of Micropulse Mp3 Cyclodiode Laser was observed in 85.7% cases. Significant mean difference was found for pre-op IOP with IOP after 3 months for right eye and left eye. Insignificant association of effectiveness was found with gender, age, type and procedure. Conclusion: Micro pulse MP3 appears to be a promising, safe alternative procedure with potential advantages as well as high level of effectiveness. Keywords: Micropulse Mp3 Cyclodiode Laser, Intraocular Pressure, Acetazolamide

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Section: Resultsmentioning

confidence: 99%

“…Yelenskiy A reported 71% effectivness. 19 Success rate varies from 40% to 80% in different studies [22][23][24] .…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Effectiveness of Micropulse MP3 Cyclodiode Laser in controlling Intraocular pressure without Acetazolamide

et al. 2020

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“…According to the sound result defined before, the success rate of our study is 90.32%, decreased to 74.19% considering the 5 cases with severe late complication, which is consistent with other studies. [9][10][11][12] Nevertheless, success rate of patients with 2/3 dose was as high as 91.67%…”

Section: Discussionmentioning

confidence: 99%

A study of the dose-response relationship for transscleral cyclophotocoagulation in refractory glaucoma

Shen²

2019

Preprint

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Background To research the efficiency of transscleral cyclophotocoagulation (TCP) in refractory glaucoma and to evaluate the dose-response relationship. Methods A retrospective analysis of the cases of 31 eyes of 31 consecutive patients with uncontrolled glaucoma who underwent TCP. Six to thirty-six months were reviewed. The main outcome measure is intraocular pressure (IOP) reduction combined with the best corrected visual acuity and complications. Calculations were performed to determine possible predictive factors that would help establish optimal treatment parameters. Results All the 31 patients felt a relieved ocular pain after TCP. Corneas of 30 eyes recovered transparent one week after TCP, except one eye with corneal epithelialization. The IOP of all patients decreased to 5mmHg-38mmHg（average is 17.93±8.00mmHg）at the end of follow-up. The main earlier complications include conjunctival burns, hyphema and mild inflammation of the anterior chamber, and the late complications were phthisis bulbi and corneal staphyloma. Final IOP was moderately negative related to the number of spots, r=-0.41(t=2.05, P<0.05), and the linear regression equation is y=27.53-0.62x (independent variable x represents the number of spots, dependent variable y represents the final IOP). To a medium extent, the final IOP was negatively correlated with the number of the audible spots, r=-0.58(t=3.75, P<0.01), and the linear regression equation is y=28.39-1.26x. Conclusion Cyclophotocoagulation is a convenient, safe and effective procedure in refractory glaucoma. The recommended parameter is about 14 spots or 8 audible spots.

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“…59 Notably, the higher-than-usual settings used by Anand et al did not appear to put patients at an increased risk of postoperative complications, as the rates of hypotony (6%), prolonged inflammation (4%), and visual decline (2%) were comparable to those reported in other studies. 37,42,44,45,47,49,54 All of the studies included in this review used the Generation 1 MP3 probe (IRIDEX Corp., Mountainview, CA) (Figure 2a). IRIDEX is currently in the process of phasing out the Generation 1 probe and shifting to the Generation 2 MP3 probe.…”

Section: Micropulse Transscleral Laser Treatment (Mp-tlt)mentioning

confidence: 99%

A Review of Cyclodestructive Procedures for the Treatment of Glaucoma

Anand

Klug

Nirappel

et al. 2020

Seminars in Ophthalmology

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Patient Outcomes Following Micropulse Transscleral Cyclophotocoagulation: Intermediate-term Results

Abstract: Our large longitudinal cohort study has provided evidence that MPTSCPC is a safe and generally effective option in the treatment of POAG up to 12 months.

Cited by 77 publications

References 24 publications

Effectiveness of Micropulse MP3 Cyclodiode Laser in controlling Intraocular pressure without Acetazolamide

Effectiveness of Micropulse MP3 Cyclodiode Laser in controlling Intraocular pressure without Acetazolamide

A study of the dose-response relationship for transscleral cyclophotocoagulation in refractory glaucoma

A Review of Cyclodestructive Procedures for the Treatment of Glaucoma

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