Patient-focused intervention to improve long-term adherence to evidence-based medications: A randomized trial

Calvert, Sara B.; Kramer, Judith M.; Anstrom, Kevin J.; Kaltenbach, Lisa A.; Stafford, Judith A.; LaPointe, Nancy M. Allen

doi:10.1016/j.ahj.2012.01.019

Cited by 78 publications

(94 citation statements)

References 35 publications

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“…For example, a nurse-led cardiovascular risk-factor counseling composed of providing patients with personalized risk assessment, and highlighting individual modifiable risk factors, had positive effect on both adherence to statins, and lipids level in primary prevention patients [21]. Intervention composed of inhospital counselling, attention to adherence barriers, communication of discharge medications to community pharmacists and physicians, and ongoing assessment of adherence by community pharmacists had a positive effect on adherence to statins in secondary prevention patients [22]. The pharmaceutical care programs resulted in lower rates of discontinuation within initial period of statin therapy [23,24].…”

Section: Discussionmentioning

confidence: 99%

An education-behavioural intervention improves adherence to statins

Kardas

2013

Open Medicine

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Section: Discussionmentioning

confidence: 99%

An education-behavioural intervention improves adherence to statins

Kardas

2013

Open Medicine

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“…At the pharmacy counter pharmacy staff has ample opportunity to inform patients about their medication and support them in using their medication properly [2][3][4]. Effective communication between providers and patients about medication use is associated with patients' satisfaction, recall of information and eventually their health status [4][5][6][7]. Research shows that patients who are sufficiently informed about the risks and benefits of their treatment, show higher adherence to their prescribed medical treatment [6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Patient–provider interaction during medication encounters: A study in outpatient pharmacies in the Netherlands

Koster

Meeteren

Dijk

et al. 2015

Patient Education and Counseling

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“…267 Enhanced in-hospital counselling on medications and adherence barriers by pharmacists coupled with communication of discharge medications to community pharmacists and physicians did not significantly improve adherence to aspirin and statins, as measured using pharmacy records. 231 In comparison, patients who received counselling sessions with a community pharmacist at the start of statin treatment demonstrated greater adherence according to pharmacy records. 271 A mailed newsletter discussing the importance of adherence and lifestyle modifications showed no improvement in adherence, as measured using physician reports.…”

Section: Cognitive-educational Interventionsmentioning

confidence: 99%

“…229 Others have selected a specific type of intervention and "tailored" that intervention to the patient. 130,153,[230][231][232][233] For example, Insel et al individualised memory strategies to improve adherence in older patients. 230 Greater focus is required on identifying the primary cause for the patient's non-adherence and tailoring interventions to these specific reasons for nonadherence.…”

Section: Self-report Adherence Scalesmentioning

confidence: 99%

“…215,218,225,226 Patient education alone has been largely unsuccessful in improving medication adherence. 15,231,[265][266][267][268] A trial involving nurse counselling via telephone increased the proportion of children with latent tuberculosis completing treatment from 65% to 94%. 269 Nurse-delivered home visits providing information on HIV and the importance of medication adherence was associated with an increased likelihood of patients reporting 100% adherence.…”

Section: Cognitive-educational Interventionsmentioning

confidence: 99%

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Improving medication adherence in patients with chronic disease using a targeted and tailored approach

Nguyen¹

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Improving adherence to medications is an opportunity that can yield great improvements in health outcomes and reducing health costs. Supporting adherence to medicines requires insight into a patient's medication-taking behaviour and their reasons for non-adherence.Adherence interventions that show most promise include multifaceted interventions, and those targeted to non-adherent patients and/or tailored to patient-specific reasons for nonadherence. To identify non-adherent patients and their reasons for non-adherence in the practice setting, I argue that we require inexpensive measures that are easy to use and can inform the discussion with patients about their adherence. Adherence scales are inexpensive, easy-to-administer and have the potential to explore both medication-taking behaviour and reasons for behaviour.The overall aim of the thesis is to determine if a targeted and tailored intervention based on a discussion informed by validated adherence scales, will improve adherence to a recently initiated cardiovascular medication. I hypothesise that targeting and tailoring an intervention to non-adherent participants based on a discussion informed by adherence scales, will improve adherence at three months as measured by the four-item Medication Adherence Questionnaire (MAQ). I will also test whether improvements in adherence at three months are sustained at six months and explore the changes in adherence and reasons for nonadherence over time.The first part of the thesis involved identifying validated adherence scales suitable for use in the intervention. A systematic review was conducted on adherence scales to explore their use and validation. We found that adherence scales measured different aspects of adherence: medication-taking behaviour, barriers to adherence and beliefs associated with adherence. Adherence scales have been validated in different disease populations and against different measures of adherence. We selected two adherence scales for our study: the MAQ and Beliefs about Medicines Questionnaire-Specific (BMQ-S). The MAQ is one of the most commonly used adherence scales that has been validated in many disease populations and against different measures of adherence including electronic monitoring.The BMQ-S has been extensively used to elicit medication beliefs associated with medication adherence and validated in a number of diseases including cardiovascular disease, asthma and depression.A randomised controlled trial was conducted to determine if a targeted and tailored intervention would improve medication adherence. Four hundred and eight patients were iii assessed for eligibility from two community pharmacies, from which 152 patients were enrolled into the study. All enrolled participants completed the MAQ, BMQ-S and Brief Illness Perceptions Questionnaire (BIPQ). There were 120 participants identified as non-adherent using the MAQ, who were randomised into an intervention or control group. The remaining 32 participants were identified as adherent. In the intervention group, the r...

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Patient-focused intervention to improve long-term adherence to evidence-based medications: A randomized trial

Cited by 78 publications

References 35 publications

An education-behavioural intervention improves adherence to statins

An education-behavioural intervention improves adherence to statins

Patient–provider interaction during medication encounters: A study in outpatient pharmacies in the Netherlands

Improving medication adherence in patients with chronic disease using a targeted and tailored approach

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