Cardiovascular diseases cause more disability and economic loss in industrialized nations than any other group ofdiseases. In previous work fNurs Res 49 (2000a) 1], most coronary artery bypass graft patients (CABG, N :225) reported unrelieved pain and received inadequate analgesics. This study proposed to evaluate a preadmission education intervention to reduce pain and related activity interference after CABG surgery. Patients (N : 406) were randomly assigned to (a) standard care or (b) standard care t pain booklet group. Data were examined at the preadmission clinic and across days 1-5 after surgery. Outcomes were pain-related interference (BPI-D, pain (MPQ-SF), analgesics (chart), concems about taking analgesics (BQ-SF), and satisfaction (American Pain Society-POQ). The impact of sex was explored related to primary and secondary outcomes. The intervention group did not have better overall pain management although they had some reduction in pain-related interference in activities (r(355) :2.54, P < 0.01) and fewer concems about taking analgesics (f(1,313):2.7, P <0.05) on day 5. Despite moderate 24-hpain intensity across 5 days, patients in both groups received inadequate analgesics (i.e. 33Vo prescribed dose). Women reported more pain and pain-related interference in activities than men. The booklet was rated as helpful, particularly by women. [n conclusion, the intervention did not result in a clinically significant improvement in pain management outcomes. [n future, an intervention that considers sex-specific needs and also involves educating the health professionals caring for these patients may influence these results.