Patient-Delivered Partner Treatment With Azithromycin to Prevent Repeated Chlamydia trachomatis Infection Among Women

Schillinger, Julia A.; Kissinger, Patricia; Calvet, Helene; Whittington, William L. H.; Ransom, Ray; Sternberg, Maya; Berman, Stuart M.; Kent, Charlotte K.; Martín, David H.; Oh, M. Kim; Handsfield, H. Hunter; Bolan, Gail; Markowitz, Lauri E.; Fortenberry, J. Dennis

doi:10.1097/00007435-200301000-00011

Cited by 233 publications

(197 citation statements)

References 23 publications

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“…According to this, patient delivered therapy has been shown to be of highest efficacy in index patients with regular partners. 24 Schillinger et al 25 conducted a comparative study assessing reinfection rates after 4 months in index women assigned to patient referral or patient delivered therapy. The two groups had a reinfection rate of 15% and 12%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Managing partners of people diagnosed with Chlamydia trachomatis: a comparison of two partner testing methods

Østergaard

Andersen²,

Jk³

et al. 2003

Sexually Transmitted Infections

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Objective: To compare the effectiveness of ''home sampling'' with that of ''office sampling'' for testing partners to men and women infected with Chlamydia trachomatis. Method: A randomised controlled effectiveness trial took place in the general community in Denmark. 1300 index women and 526 index men (>18 years) with a positive test result for C trachomatis were identified. Of these, 414 index women and 148 index men gave implied consent. Index patients were randomly assigned to provide their partner(s) through the past 12 months with either (1) a kit by which partner(s) could be tested by home sampling, or (2) a kit by which partner(s) could only be tested by seeing a healthcare professional (office sampling). The main outcome measure was the proportion of index patients who had at least one partner tested for C trachomatis. Results: The proportion of index women with at least one partner tested was higher in the home sampling group (0.26) than in the office group (0.12) (difference 0.14; 95% CI 0.10 to 0.19; p,0.0001) and so it was for index men (0.15 v 0.03; difference 0.12; 95% CI 0.07 to 0.16; p,0.0001). Also the proportion of index women for whom at least one partner was identified as infected was higher in the home sampling group compared with the office group (0.11 v 0.07, p = 0.01). The corresponding figures for index men were 0.06 v 0.01, p = 0.02. Conclusion: The effectiveness of partner testing is higher when partners of C trachomatis infected patients are offered home sampling than when they are offered office sampling. P opulation based surveys have found urogenital Chlamydia trachomatis infection rates between 3% and 6% in young men and women,

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Section: Discussionmentioning

confidence: 99%

Managing partners of people diagnosed with Chlamydia trachomatis: a comparison of two partner testing methods

Østergaard

Andersen²,

Jk³

et al. 2003

Sexually Transmitted Infections

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“…All sex partners in the past 60 days should be referred for evaluation, testing, and presumptive treatment if chlamydia, gonorrhea, or trichomoniasis was identified or suspected in the women with cervicitis. EPT or other effective partner referral strategies (see Partner Services) are alternative approaches to treating male partners of women who have chlamydia or gonococcal infection (93)(94)(95). To avoid reinfection, sex partners should abstain from sexual intercourse until they and their partner(s) are adequately treated.…”

Section: Cervicitismentioning

confidence: 99%

“…Compared with standard patient referral of partners, this approach to therapy, which involves delivering the medication itself or a prescription, has been associated with decreased rates of persistent or recurrent chlamydia (93)(94)(95). Providers should also provide patients with written educational materials to give to their partner(s) about chlamydia in general, to include notification that partner(s) have been exposed and information about the importance of treatment.…”

Section: Treatment-treatingmentioning

confidence: 99%

“…Arrangements should be made to link male partners to care. If linkage is delayed or unlikely, EPT and enhanced referral are alternative approaches to treating male partners of women who have chlamydia or gonococcal infections (see Partner Services) (93,94). Partners should be instructed to abstain from sexual intercourse until they and their sex partners have been adequately treated (i.e., until therapy is completed and symptoms have resolved, if originally present).…”

Section: Follow-upmentioning

confidence: 99%

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Sexually Transmitted Diseases Treatment Guidelines 2002

2002

PsycEXTRA Dataset

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SummaryThese guidelines for the treatment of persons who have or are at risk for sexually transmitted diseases (STDs) were updated by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta on April 30-May 2, 2013. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2010 (MMWR Recomm Rep 201059 [No. RR-12]). These updated guidelines discuss 1) alternative treatment regimens for Neisseria gonorrhoeae; 2) the use of nucleic acid amplification tests for the diagnosis of trichomoniasis; 3) alternative treatment options for genital warts; 4) the role of Mycoplasma genitalium in urethritis/cervicitis and treatment-related implications; 5) updated HPV vaccine recommendations and counseling messages; 6) the management of persons who are transgender; 7) annual testing for hepatitis C in persons with HIV infection; 8) updated recommendations for diagnostic evaluation of urethritis; and 9) retesting to detect repeat infection. Physicians and other health-care providers can use these guidelines to assist in the prevention and treatment of STDs.

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“…Printed partner referral cards have been used in a range of circumstances, and appear to be effective in promoting notification within heterosexual partnerships (19,20). However, evidence of the impact of referral cards in developing country settings is limited, and their use within MSM partnerships has not, to our knowledge, been evaluated in any previous randomized controlled trials (RCTs) (21)(22)(23).…”

Section: Introductionmentioning

confidence: 99%

Traditional and Web-Based Technologies to Improve Partner Notification Following Syphilis Diagnosis Among Men Who Have Sex With Men in Lima, Peru: Pilot Randomized Controlled Trial (Preprint)

Clark¹,

Segura²,

Oldenburg³

et al. 2018

Preprint

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Patient-Delivered Partner Treatment With Azithromycin to Prevent Repeated Chlamydia trachomatis Infection Among Women

Abstract: Patient-delivered partner treatment for prevention of repeated infection among women is comparable to self-referral and may be an appropriate option for some patients.

Cited by 233 publications

References 23 publications

Managing partners of people diagnosed with Chlamydia trachomatis: a comparison of two partner testing methods

Managing partners of people diagnosed with Chlamydia trachomatis: a comparison of two partner testing methods

Sexually Transmitted Diseases Treatment Guidelines 2002

Traditional and Web-Based Technologies to Improve Partner Notification Following Syphilis Diagnosis Among Men Who Have Sex With Men in Lima, Peru: Pilot Randomized Controlled Trial (Preprint)

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