Patient characteristics associated with failure of tuberculosis prevention

Menzies, Dick; Adhikari, Nilaramba; Tannenbaum, Terry

doi:10.1016/s0962-8479(96)90094-5

Cited by 8 publications

(11 citation statements)

References 28 publications

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“…Similar observation that noncompliance was maximum in middle age group were also reported by Sophia et al 65.2% But Menzis et al found that older subjects were less compliant. 6,7 In the present study compliance was higher among female 83.5% than male 78.1%. In other words noncompliance was more prevalent among male patients (21.9%).…”

Section: Discussionsupporting

confidence: 44%

An assessment of treatment compliance among patients on DOTS under revised national tuberculosis control programme in district Rewa, Madhya Pradesh, India

Rai

Kushwah

Singh

et al. 2015

Int J Community Med Public Health

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INTRODUCTIONTuberculosis (TB) is a major cause of illness and death worldwide, especially in Asia and Africa. Globally, 9.2 million new cases and 1.7 million deaths from TB occurred in 2006, of which 0.7 million cases and 0.2 million deaths were in HIV-positive people. In India 1.8 million tuberculosis cases occur annually, accounting for one-fifth of the world's new TB cases and two-thirds of the cases in the South-East Asia Region. This makes India the highest TB burden country in the world. In the year 2006, annual performance of revised national tuberculosis control programme (RNTCP) in India, in terms of cure rate of new smear positive patients was 84%, default rate was 6.4% while in Madhya Pradesh it was 82% and 7.6% respectively. Rewa district have poor performance as compare to national level. 2Considering the above facts, this study was a small attempt to find out the compliance to DOTS and associated reasons responsible for non-compliance in the district. ABSTRACTBackground: India is the highest TB burden country in the world. In the year 2006, annual performance of revised national tuberculosis control programme (RNTCP) in India, in terms of cure rate of new smear positive patients was 84%, default rate was 6.4% while in Madhya Pradesh it was 82% and 7.6% respectively. Rewa district have poor performance as compare to national level. Non-adherence with treatment has been recognized as an important factor responsible for low cure rate and high incidence of drug resistant TB. The objective of study was to find out the compliance rate with DOTS and associated factors responsible for non-compliance in the district. Methods: The present observational study was carried out at fifteen selected DMC cum DOTS centers of Rewa district, M.P. Results: Of the 337 patients interviewed, majority of patients 270 (80.11%) complied and 67 (19.88%) did not comply to treatment. The main reasons for non-compliance were false perception of having their disease cured because they felt well with initial treatment 26 (38.81%), side effects of drugs 23 (34.33%), anxiety of loss of wages 9 (13.43%) and Migration of patients 7 (10.44%). Conclusions: Repeated counselling and motivation of noncompliant patients would be helpful to reduce noncompliance to treatment.

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Section: Discussionsupporting

confidence: 44%

An assessment of treatment compliance among patients on DOTS under revised national tuberculosis control programme in district Rewa, Madhya Pradesh, India

Rai

Kushwah

Singh

et al. 2015

Int J Community Med Public Health

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“…41 Another difference was that unstable housing predicted the first visit to the TB Clinic, while stable housing predicted therapy completion in those who went to the TB Clinic. The former may be explained by multiple messages regarding TB provided in homeless shelters and clinics serving the home-less; the latter may reflect consistency with adherence literature, 35,40 pointing to social support and additional resources among the stably housed.…”

Section: Completion Of Therapy For Ltbimentioning

confidence: 86%

“…Findings from this study differ from the literature in that few of the factors traditionally associated with nonadherence influenced the outcomes of this study. Such general factors include homelessness; substance abuse; lack of family or social support; migrant status; unemployment or low income; low education and minority status [35][36][37][38][39][40] ; age and male sex, 37,38 which have been inconsistent predictors 36,37,40 ; and specifically related to TB, no prior medication use, knowledge, and beliefs about medications, cultural factors, and limited access to care. 38,[41][42][43][44][45][46][47][48] Incarcerated persons share many of the factors identified as barriers, but in this study, time in the United States and stable housing were the only important additional predictors of adherence.…”

Section: Completion Of Therapy For Ltbimentioning

confidence: 99%

Randomized Controlled Trial of Interventions to Improve Follow-up for Latent Tuberculosis Infection After Release From Jail

White

Tulsky²,

Goldenson³

et al. 2002

Arch Intern Med

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“…(1011) Kumar et al . observed maximum default in the 35-44-year age group (25.4%), followed by the patients aged above 45 years (18.1%).…”

Section: Discussionmentioning

confidence: 99%

Noncompliance to DOTS: How it can be decreased

Mittal¹,

Gupta²

2011

Indian J Community Med

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Background:Tuberculosis is a communicable disease requiring prolonged treatment.The therapeutic regimens as recommended by WHO have been shown to be highly effective for both preventing and treating tuberculosis but poor adherence to medication is a major barrier to its global control.Aim:The aim was to elicit reasons of treatment default from a cohort of tuberculosis patients treated under Directly Observed Treatment Short course chemotherapy.Settings and design:Thiscross-sectional study was conducted in Agra city using the multistage simple random sampling.Materials and Methods:A total of 900 patients attending DOTS centres of the selected designated microscopy centers (DMCs) were included in the study from January 2007 onward. The information was obtained from treatment cards of patients and those who defaulted were further interviewed in community.Statistical analysis:Chi-square test was applied to observe the significance of association using the Epi Info software (version 6).Results:More default was observed among the age group of >45 years (22.8%), male (18.7%), business men (30.6%), and retired and unemployed patients. Other factors associated with higher default were pulmonary disease (18.2%), retreatment cases (30.6%) and category II patients (26.4%). Important reasons of default were side effects following medication (43.2%), improvement in symptoms (14.4%), and lack of time (13.5%). No relief in symptoms and lack of awareness were other important reasons.Conclusions:Noncompliance was found to be mainly due to side effects of medicines, lack of time, and unawareness. So educating the patient about various aspects of tuberculosis and some measures to decrease side effects are of utmost importance.

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Patient characteristics associated with failure of tuberculosis prevention

Cited by 8 publications

References 28 publications

An assessment of treatment compliance among patients on DOTS under revised national tuberculosis control programme in district Rewa, Madhya Pradesh, India

An assessment of treatment compliance among patients on DOTS under revised national tuberculosis control programme in district Rewa, Madhya Pradesh, India

Randomized Controlled Trial of Interventions to Improve Follow-up for Latent Tuberculosis Infection After Release From Jail

Noncompliance to DOTS: How it can be decreased

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