Patient Characteristics and Emergency Department Factors Associated with Survival After Sudden Cardiac Arrest in Children and Young Adults: A Cross-Sectional Analysis of a Nationally Representative Sample, 2006–2013

Sakai‐Bizmark, Rie; Friedlander, Scott; Marr, Emily H.; Mena, Laurie A.; Corral, Ismael; Chang, Ruey‐Kang R.

doi:10.1007/s00246-018-1886-8

Cited by 10 publications

(5 citation statements)

References 50 publications

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“…This patient presented to the ED after an out-of-hospital cardiac arrest. The estimated incidence of sudden cardiac death (SCD) or sudden cardiac arrest (SCA) in children and young adults varies widely from 1.1 to 6.9 per 100,000 person-years, with a mortality rate reaching 89.6% [7][8][9]. Given the high mortality rate, further investigation has been done to evaluate the underlying etiology of the deaths.…”

Section: Discussionmentioning

confidence: 99%

Classic Presentation of Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report

Hill¹,

Schoonover²,

Benner³

et al. 2022

Cureus

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Syncope is a common reason for children and adolescents to seek care in the emergency department. Often syncopal episodes are benign and most commonly due to a vasovagal event. Occasionally an underlying cardiac arrhythmia is responsible. We present a case report of a 17-year-old male who collapsed during an emotional event and went into cardiac arrest. Emergency department evaluation including imaging, laboratory studies, and EKG indicated the cause of cardiac arrest was likely a primary cardiac arrhythmia. An initial clinical diagnosis of catecholaminergic polymorphic ventricular tachycardia (CPVT) was made based on symptom onset during an emotional event, family history of sudden cardiac death, patient age, past episodes of chest pain and palpitations, absence of structural heart defect, and lack of EKG changes after the return of spontaneous circulation (ROSC). The diagnosis was later confirmed with genetic testing. The patient was started on a beta-blocker and a subcutaneous implantable cardioverter-defibrillator (S-ICD, Boston Scientific, Marlborough, MA) was placed. Given the rarity of this condition, this diagnosis is often missed, which contributes to increased mortality rates. In children and young adults presenting with syncope without clear etiology in the presence of high-risk features, further evaluation should be performed including referral to cardiology to rule out chronic cardiac arrhythmias.

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Section: Discussionmentioning

confidence: 99%

Classic Presentation of Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report

Hill¹,

Schoonover²,

Benner³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…4 Demographic risk factors for SCDY include infancy and adolescence, Black race, and male biological sex. [5][6][7][8][9][10] Further research into these risk factors could result in future interventions-economic, environmental, and educational-to address them. 7 Additional individual risk factors include athletic participation and physiologic risks.…”

Section: ■ Epidemiology and Risk Factorsmentioning

confidence: 99%

Sudden cardiac death in the young

Doucette

Rosenblum

2023

The Nurse Practitioner

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:NPs can identify risk for sudden cardiac death in children during physical exams to prevent tragedy. The updated American Academy of Pediatrics 2021 policy statement on this issue provides guidance on using a combination of elements to determine and manage risk, including the organization's own 4-question screening tool, the American Heart Association 14-Element Preparticipation Cardiovascular Screening of Young Competitive Athletes, personal history, family history, physical exam, ECG, and cardiology referral as indicated.

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“…The primary outcome was the ROSC after the cardiopulmonary resuscitation and the number of adrenaline doses that were administered, and the secondary outcome was the neurological outcome at 1 month after the OHCA in relation to the number of adrenaline doses that were administered, as reported in previous study (1,(14)(15)(16)(17).…”

Section: Measurements and De Nitionsmentioning

confidence: 99%

Correlation of Adrenaline Doses With the Outcome of Paediatric Out-of-hospital Cardiac Arrest: Secondary Analysis of the SOS-KANTO 2012 Study

Ishihara

Kondo

Sueyoshi

et al. 2020

Preprint

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Background Out-of-hospital cardiac arrest (OHCA) is very rare in the paediatric population, with an annual incidence of 2-9 cases per 1,000,000 children. The predictive factors for survival included a shorter interval between the time of arrest and hospital arrival, a palpable pulse on presentation in the emergency department (ED), a shorter duration of resuscitation in the ED, and the administration of fewer doses of adrenaline in the ED. This study was conducted to evaluated the interrelationship between the paediatric OHCA outcome and the number of adrenaline doses administered during resuscitation. Methods The SOS-KANTO 2012 study had enrolled all OHCA patients who were transported to the participant hospitals by emergency medical service personnel. After screening the available data, we included paediatric OHCA patients (aged ≤ 18 years) in this study. The primary outcome was the return of spontaneous circulation (ROSC) and the number of adrenaline doses that were administered, and the secondary outcome was the neurological outcome at 1 month after the OHCA in relation to the number of adrenaline doses. Results Two hundred sixty-seven patients were included in the final analyses. During CPR, 62 and 205 paediatric patients did and did not achieve ROSC, respectively. Patients who survived to one month after the OHCA received fewer adrenaline doses than patients who died, although there was no significant intergroup difference (3 [1.75-5.25], vs. 4 [2.5-6], p=0.319). Patients with a good neurological outcome (PCPC 1-2) received fewer doses of adrenaline than those with an unfavourable neurological outcome (PCPC 3-6), but intergroup difference was not significant. Fewer doses of adrenaline were associated with an improved rate of successful ROSC (odds ration = 0.80,95% confidence interval = 0.69-0.92, p<0.01). Conclusion The present study reports associations of the neurological outcomes with adrenaline doses in paediatric patients with OHCA. More than three adrenaline doses were associated with poor neurological outcome, and a favourable outcome occurred infrequently. By using information that was only available up to 1 month after the OHCA, we found that a higher number of adrenaline doses was associated with poor neurological outcome.

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Patient Characteristics and Emergency Department Factors Associated with Survival After Sudden Cardiac Arrest in Children and Young Adults: A Cross-Sectional Analysis of a Nationally Representative Sample, 2006–2013

Cited by 10 publications

References 50 publications

Classic Presentation of Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report

Classic Presentation of Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report

Sudden cardiac death in the young

Correlation of Adrenaline Doses With the Outcome of Paediatric Out-of-hospital Cardiac Arrest: Secondary Analysis of the SOS-KANTO 2012 Study

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