Nationally and within Colorado, the number of persons experiencing homelessness (PEH) has continued to rise in recent years, with over half a million PEH counted on a single night in 2022. Our community-partnered study aimed to combine existing data from electronic health records, the justice system, and case management records to create a multidimensional measure for success in permanent supportive housing (PSH), and identify individual factors associated with housing success. The partnership included healthcare experts, housing providers, and a dedicated community advisory panel of persons with lived experience to guide and conduct the study. Metrics of housing success were expanded beyond housing retention to include multiple life domains, including engagement in care, wellness, adherence to housing rules and safety, level of care match, and overall success. Our analysis matched individual records across disparate data systems, which contributed to a loss in data fidelity and an inability to identify predictors associated with housing success. Our findings revealed the adaptability of case managers to harness additional resources for clients and highlights the need for systematic collection of dynamic indicators of client progress over time. This study is a clarion call for a social-health information exchange, which would support an informed, equitable, and just approach to the provision and support of PSH for PEH. Establishment of a robust cross-sector and community partnership through this study has provided the foundation for ongoing work dedicated to improving access to and success within supportive housing.