Patient Blood Management in intensive care patients

Hof, Lotta; Choorapoikayil, Suma; Meybohm, Patrick; Zacharowski, Kai

doi:10.1097/mcc.0000000000000880

Cited by 7 publications

(3 citation statements)

References 66 publications

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“…PBM approaches have expanded from the perioperative setting into other realms such as obstetrics [8], non-operative settings such as liver-disease [9], and the intensive care unit (ICU) [10]. In the perioperative setting, PBM has been shown to increase optimization of perioperative anemia, reduce the administration of blood products, and decrease hospital length of stay, however the nuance and effect of these approaches in the ICU setting are not well described in the literature [11••].…”

Section: Introductionmentioning

confidence: 99%

Patient Blood Management for the Critically-Ill Patient

Littlejohn,

Shen,

Srivastava

et al. 2024

Curr Anesthesiol Rep

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Purpose of the Review Anemia in the critically ill is both insidious and highly prevalent; and has been implicated in poor outcomes in patients with and recovering from critical illness. Patient-oriented approaches to blood management (PBM) are gaining momentum and have widespread applications as a superior approach to anemia. The volume of publications pertaining to PBM has dramatically increased in the past 4 years, warranting further review of emerging paradigms in the ICU. Recent Findings IV iron alone and in conjunction with erythropoietin are being studied prospectively. Factor concentrates are used more frequently, and both point of care and viscoelastic testing algorithms have been shown to reduce utilization of blood products. Both whole blood and thrombopoietin also show promise in reducing transfusions. Summary Careful attention to PBM approaches has the potential to improve the quality and reduce the cost of care of patients in the ICU. Significant work remains, especially in the areas of education of care teams on the importance of reducing phlebotomy and updating knowledge of current indications for therapies aimed at increasing hemoglobin levels and reducing blood product transfusions.

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Section: Introductionmentioning

confidence: 99%

Patient Blood Management for the Critically-Ill Patient

Littlejohn,

Shen,

Srivastava

et al. 2024

Curr Anesthesiol Rep

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“…In their study, Hof L. et al recommend taking patientbased measures (preventing anemia, reducing blood loss, etc.) for blood management of intensive care patients, especially due to the decrease in global blood donations owing to the pandemic (6). Ultimately, we aimed to evaluate how our blood center was affected by the pandemic regarding blood products by blood types.…”

Section: Introductionmentioning

confidence: 99%

Distribution of pre- and mid-pandemic transfusions by blood types

Yılmaz

ZERDE

Alay

et al. 2022

Journal of Health Sciences and Medicine

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Introduction: COVID-19 disease spread rapidly worldwide, causing a pandemic. In this study, we aimed to explore the distribution of blood products in our blood center before and during the pandemic by blood type. Material and Method: In this study, we retrospectively analyzed 4,271 blood products (1,290 patients) transfused before and during the pandemic through the medical records of Kastamonu Training and Research Hospital Blood Transfusion Center. Moreover, we investigated the associations between transfusions and age, sex, blood type, and COVID-19 infection. Results: The findings revealed that the majority of the patients receiving transfusions both before and during the pandemic were A Rh (+) (41.4%). Besides, the rates of those with O Rh (+) were 28.8% and 28.7% during the pandemic. In addition, 37 products (28 erythrocyte suspensions, 7 fresh frozen plasma, 2 pooled platelet suspensions) were transfused on 17 patients with confirmed COVID-19. Conclusion: Transfusions have an important place in the treatment of critically ill patients. The blood type A Rh (+) was previously shown to be associated with an increased risk of COVID-19 infection. In this study, although we realized that products of blood type A were mostly used in general transfusions, transfusions in the pandemic were performed predominantly with blood products of infected patients with blood type O. The modern world is more likely to encounter further pandemics in the future. We think that each region should evaluate its own centers.

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“…In this context RBCT should be viewed as a treatment of last resort in anemic critically ill patients. Anemia management should instead be focused on causal anemia treatment and minimization of patient blood loss, both important elements of patient blood management [ 2 ]. On the other hand, anemia in critically ill patients may lead to, among other consequences, prolonged weaning from the respirator, acute kidney injury, myocardial ischemia [ 3 ], the need for RBCT.…”

mentioning

confidence: 99%