BACKGROUND Patient activation is critical to improving patient selfmanagement and reducing avoidable emergency department visits and hospitalizations. Less recognized, however, is that social disadvantage (e.g., poverty, minority race, born outside USA, non-English speaking) contributes to disparities in health care through lower patient activation. 1 HIV is a prime example where low patient activation among socially disadvantaged persons living with HIV (PLWH) contributes to disparities in adherence, 2, 3 viral suppression, 4, 5 and ultimately, to disparities in HIV treatment outcomes, 6-8 such as hospitalizations and mortality. 9, 10 Compared to non-Latino white and/or more affluent PLWH, poor and minority PLWH miss more office visits, 11 ask fewer questions during their visits, 12 report less confidence in self-management and more frequently miss doses, 13 or stop taking their antiretroviral therapy. 14 Death from HIV-related causes represents a top ten leading cause of death among Blacks and Latinos ages 20-54 years. 15 Among Blacks ages 35-44 years, HIV ranks in the top five causes of death. 15 Therefore, improvements in patient Electronic supplementary material The online version of this article (