Paths to Panic Disorder/Agoraphobia: An Exploratory Analysis From Age 3 to 21 in an Unselected Birth Cohort

Craske, Michelle G.; Poulton, Richie; Tsao, Jennie C.I.; Plotkin, David

doi:10.1097/00004583-200105000-00015

Cited by 95 publications

(61 citation statements)

References 31 publications

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“…[4,[7][8][9] A recent longitudinal study also found that anxiety and depressive disorders were associated with a higher risk of subsequent development of asthma.…”

Section: Nih Public Accessmentioning

confidence: 95%

“…[6] Recent research suggests that youth with asthma also have a high rate of other depressive and anxiety disorders. [4,[7][8][9] A recent longitudinal study also found that anxiety and depressive disorders were associated with a higher risk of subsequent development of asthma. [10] While these epidemiologic studies are suggestive of an association between anxiety and depressive disorders and asthma, conclusions are limited by the fact that only one study had information on physician diagnosis of asthma, as well as other medical comorbidities, there was no or limited data on asthma severity, asthma treatments (some of which can cause increased anxiety), and health risk behaviors such as smoking [11].…”

mentioning

confidence: 99%

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The Prevalence of DSM-IV Anxiety and Depressive Disorders in Youth with Asthma Compared with Controls

Katon

Lozano

Russo

et al. 2007

Journal of Adolescent Health

228

158

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Purpose-To determine the prevalence of anxiety and depressive disorders in youth with asthma compared to a control sample of youth and to determine the sociodemographic and clinical characteristics associated with having ≥1 anxiety/depressive disorders among youth with asthma.Methods-A telephone interview was offered to all youth aged 11 to 17 with asthma (N=781) and a random sample of similar aged controls (N=598) enrolled in a Health Maintenance Organization (HMO). The C-DISC-4.0 was used to diagnose anxiety and depressive disorders and reliable and valid questionnaires were used to assess severity of anxiety and depressive symptoms. Automated diagnostic, pharmacy and health utilization data were used to measure asthma treatment intensity, asthma severity and non-asthmatic medical comorbidity. One parent was interviewed to assess sociodemographic variables, child/adolescent psychiatric symptoms and to confirm the asthma diagnosis.Results-16.3% of youth with asthma compared to 8.6% of youth without asthma met DSM-IV criteria for ≥1 anxiety and depressive disorders (OR = 1.92, 95% CI 1.13-3.28). Independent factors associated with a significantly higher likelihood of meeting criteria for ≥1 anxiety or depressive disorders included female gender [OR = 1.96 (95% CI 1.27, 3.03)], living in a single parent household, [OR = 1.96 (95% CI 1.26, 3.07)], more parent-reported externalizing behaviors [OR = 1.03 (95% CI 1.01, 1.05)], more recent diagnosis of asthma [OR = 0.94 (95% CI 0.89, 0.98)], and more impairment on the asthma physical health scale [OR = 0.95 (95% CI 0.94, 0.96)].Conclusions-Youth with asthma have an almost two-fold higher prevalence of comorbid DSM-IV anxiety and depressive disorders compared to control youth. Clinical factors associated with meeting criteria for ≥1 anxiety and depressive included more recent asthma diagnosis, more impairment on the asthma physical health scale and increased externalizing behaviors. Medicine, 1959 NE Pacific St., Seattle, WA 98195-6560, PH: 206-543-7177, Fax: 206-221-5414, E-Mail: wkaton@u.washington.edu. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Cross-sectional studies have repeatedly found an increased prevalence of panic disorder among youth with asthma. [1][2][3][4][5] A large family history study also recently reported that first degree relatives of patients with panic disorder had a significantly higher prevalence of asthma and chronic obstructive lung disease compared to a control group without panic disorder. NIH Public Access[6] Recent research suggests that youth with asthma also have a high rate of ot...

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“…[4,[7][8][9] A recent longitudinal study also found that anxiety and depressive disorders were associated with a higher risk of subsequent development of asthma.…”

Section: Nih Public Accessmentioning

confidence: 95%

mentioning

confidence: 99%

The Prevalence of DSM-IV Anxiety and Depressive Disorders in Youth with Asthma Compared with Controls

Katon

Lozano

Russo

et al. 2007

Journal of Adolescent Health

228

158

View full text Add to dashboard Cite

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“…However, similar results have been found through objective measures of temperament (Craske et al, 2001). …”

Section: Anxiety In Individuals With Williams Syndromesupporting

confidence: 81%

“…In a longitudinal study of temperament and behavior problems, Rende (1993) found that the parent-rated temperamental trait of emotionality at ages 1 -4 years was significantly associated with and predicted anxiety/depression at age 7 years. Similarly, Craske, Poulton, Tsao, and Poulton (2001) found that temperament aspects of negative reactivity assessed at age 3 years through behavioral observations (measuring emotional reactivity, fearfulness, shyness, and separation anxiety) were associated with Agoraphobia/Panic Disorder at age 18 -21 years. Grant, Bagnell, Chambers, and Stewart (2009) found that difficult temperament at age 2 -3 years was associated with caregiver-reported anxiety symptoms at ages 6 -7 and 8 -9 years, while fearful distress at age 2 -3 years was associated with caregiver-reported anxiety at age 8 -9 years.…”

Section: Anxiety In Individuals With Williams Syndromementioning

confidence: 87%

Anxiety in children with Williams syndrome : association with negative reactivity, self-regulation, and sensory modulation.

Crawford-Zelli

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“…Unsurprisingly, numerous studies found that panic disorder and lung disease commonly occur together (Goodwin and Eaton 2003;Goodwin et al, 2004;Katon et al, 2004;Nascimento et al, 2002;Klein, 2001;RoyByrne et al, 2006;Valenca et al, 2006;Wingate and Hansen-Flaschen, 1997;Yellowlees and Kalucy, 1990;Yellowlees et al, 1988). More specifically, we wrote, "early lung disease, including asthma and COPD may predispose to PD (Craske et al, 2001;Goodwin and Eaton, 2003;Hasler et al, 2005;Karajgi et al, 1990;Perna et al, 1997;Verburg et al, 1995), or present solely with panic symptoms (Edlund et al, 1991;Sietsema et al, 1987). Asthma and PD are both characterized by acute episodes, salient respiratory symptoms and anxiety with avoidance of situations related to acute attacks (Klein, 1993;Yellowlees and Kalucy, 1990).…”

Section: Panic and Comorbid Conditionsmentioning

confidence: 99%

Lifelong Opioidergic Vulnerability Through Early Life Separation: A Recent Extension of the False Suffocation Alarm Theory of Panic Disorder

Preter¹

2016

Panic Disorder

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We briefly reference previous material on Klein's suffocation false alarm theory (SFA) of panic disorder (Klein, 1993) and its amplification in 2008 (Preter andKlein, 2008). We then discuss a recent finding showing a fundamental difference in opioidergic reactivity to a naloxone challenge in psychiatrically and medically healthy adults, based on the presence or absence of childhood separation/parental loss.In 1993, Klein published the original SFA theory of panic disorder (Klein, 1993), attempting to integrate the multiplicity of apparently unrelated clinical and laboratory observations. We posited "that a physiologic misinterpretation by a suffocation monitor misfires an evolved suffocation alarm system. This produces sudden respiratory distress followed swiftly by a brief hyperventilation, panic, and the urge to flee. Carbon dioxide hypersensitivity is seen as due to the deranged suffocation alarm monitor. If other indicators of potential suffocation provoke panic, this theoretical extension is supported." In the original paper, we tested "the theory by examining Ondine's curse as the physiologic and pharmacologic converse of panic disorder, splitting panic in terms of symptomatology and challenge studies, reevaluating the role of hyperventilation, and reinterpreting the contagiousness of sighing and yawning, as well as mass hysteria." (Klein, 1993) Original SFA focused on relating the observed lactate and carbon dioxide hypersensitivity in panic disorder to a putative dysfunction in a hypothesized suffocation alarm. At the time, the underlying pathophysiology that might connect the apparent disparate "phenomena of panic during relaxation and sleep, late luteal phase dysphoric disorder, pregnancy, childbirth, pulmonary disease, separation anxiety, and treatment", was unknown.

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Paths to Panic Disorder/Agoraphobia: An Exploratory Analysis From Age 3 to 21 in an Unselected Birth Cohort

Cited by 95 publications

References 31 publications

The Prevalence of DSM-IV Anxiety and Depressive Disorders in Youth with Asthma Compared with Controls

The Prevalence of DSM-IV Anxiety and Depressive Disorders in Youth with Asthma Compared with Controls

Anxiety in children with Williams syndrome : association with negative reactivity, self-regulation, and sensory modulation.

Lifelong Opioidergic Vulnerability Through Early Life Separation: A Recent Extension of the False Suffocation Alarm Theory of Panic Disorder

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