Current Opinion in Hematology volume 17, issue 5, P418-423 2010 DOI: 10.1097/moh.0b013e32833c07d3 View full text
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Mark R Looney, Brian M Gilliss, Michael A Matthay

Abstract: TRALI requires an immune priming step followed by transfusion of a blood product with either leukocyte allo-antibodies or biological response modifiers. TRALI invokes an acute immune response dominated by neutrophils interacting with platelets and the lung endothelium.