Pathophysiology of Posttraumatic Ankle Osteoarthritis: A Multicenter Perspective
Alexandre Leme Godoy-Santos,
Cesar de Cesar Netto,
Simone Santini
et al.
Abstract:Besides the acute injury and trauma-induced macroscopic alterations, the evolution to posttraumatic ankle osteoarthritis (PTOA) is a complex process progressing at the tissue and molecular level. Furthermore, changes in the molecular pathways affect chondrocyte viability. Treatment modalities for PTOA focal or confined disease include innovative techniques. Objective: Our purpose is to increase medical awareness based on scientific evidence of pathophysiology, molecular biology, and treatment of post-traumatic… Show more
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