Pathophysiological Mechanisms of Headache in Patients With<scp>HIV</scp>

Joshi, Shivang; Cho, Tracey A.

doi:10.1111/head.12356

Cited by 17 publications

(14 citation statements)

References 42 publications

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“…It has been suggested that HIV may provoke headaches through mechanisms that resemble the pathophysiology of migraine, such as increased glutamate levels and diminished serotonin levels. 12 This could explain the high frequency of migraine among our patients. We found significantly more migraine among those individuals whose headaches started after they were diagnosed as HIV-positive, corroborating with a possible promigraine effect of HIV.…”

Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 73%

“…11 The mechanisms that might contribute toward this include release of inflammatory cytokines, alteration of the metabolism of cerebral serotonin during viral infection, and increased levels of cerebral glutamate caused by viral proteins such as Tat and gp120. 12 There are divergences in the literature regarding whether HIV infection might worsen primary headaches, [5][6][7] what headache pattern is most commonly encountered, [5][6][7][8] and whether lower CD4 levels are associated with greater severity of headache. 7,9 Most studies that have evaluated patients with headaches and HIV were conducted among patients at an advanced stage of the disease.…”

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confidence: 99%

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HIV and Headache: A Cross‐Sectional Study

2017

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Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 73%

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confidence: 99%

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HIV and Headache: A Cross‐Sectional Study

2017

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“…Particular attention, however, should be paid to immune system-compromised and HIV-positive patients [37]. Intracranial pathology is found in cases of new-onset headache in up to 82 % of these patients [38,39] ( • " Fig. 6).…”

Section: Symptomologymentioning

confidence: 99%

Radiological Diagnosis and Differential Diagnosis of Headache

Langner¹,

Kirsch

2015

Fortschr Röntgenstr

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Headache is very common and affects almost everyone at some point. It is one of the most common disorders that leads patients to see their physician. All different forms have the nociception via trigeminal nerve fibers in common. Beside the clinical course headaches are classified as either primary or secondary, with the latter having an identifiable structural or biochemical cause. Imaging has a low diagnostic yield in primary headache but play an important role in the differential diagnosis of secondary forms. An overview of different forms of secondary headache is given, outlining diagnostic procedures and the morphologic imaging features of each syndrome. Key points: ??Headache can be differentiated in primary and secondary forms. ??Imaging plays an important role in differential diagnosis of secondary forms. ??Imaging should be performed in patients with concomitant systemic or neurologic symptoms. Citation Format: ??Langner S, Kirsch M, Hosten N Radiological Diagnosis and Differentialdiagnosis of Headache. Fortschr R?ntgenstr 2015; 187: 879???891

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“…Headache is a common human experience that does not spare those also infected with human immunodeficiency virus (HIV). This issue of Headache Currents includes 2 reviews on headache in HIV‐infected patients, one focusing on clinical aspects and the other on pathogenesis . The authors emphasize that headaches are more likely to be secondary in HIV‐infected patients than in the general population, particularly in HIV‐infected individuals who are not treated with combination antiretroviral therapy (CART) or who, despite treatment, remain significantly immunosuppressed.…”

mentioning

confidence: 99%