Pathophysiologic Mapping of Chronic Liver Diseases With Longitudinal Multiparametric MRI in Animal Models
Ferhan Baskaya,
Teresa Lemainque,
Barbara Klinkhammer
et al.
Abstract:Objectives
Chronic liver diseases (CLDs) have diverse etiologies. To better classify CLDs, we explored the ability of longitudinal multiparametric MRI (magnetic resonance imaging) in depicting alterations in liver morphology, inflammation, and hepatocyte and macrophage activity in murine high-fat diet (HFD)– and carbon tetrachloride (CCl4)–induced CLD models.
Materials and Methods
Mice were either untreated, fed an HFD for 24 weeks, or injected with CCl… Show more
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