Pathophysiologic effects of prolonged laparoscopic operation

Wolf, J. Stuart

doi:10.1002/(sici)1098-2388(199603/04)12:2<86::aid-ssu2>3.0.co;2-#

Cited by 25 publications

(20 citation statements)

References 77 publications

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“…Insufflation of CO 2 into the colon could lead to arterial CO 2 retention and subsequent acidosis because CO 2 acts as an acid in the human body [14,15].Theoretically, the development of severe acidosis can subsequently lead to cardiac arrhythmia and circulatory collapse. Furthermore, it is well known that sedatives can lead to impaired respiration (hypoventilation and hypoxemia), causing changes in PCO 2 and other metabolic parameters [8].…”

Section: Discussionmentioning

confidence: 99%

Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective study

Kikuchi

Saito

et al. 2010

Surg Endosc

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Section: Discussionmentioning

confidence: 99%

Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective study

Kikuchi

Saito

et al. 2010

Surg Endosc

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“…4). CO 2 is absorbed through the peritoneal surface into the bloodstream, leading to elevation of arterial CO 2 , and is eliminated by ventilation in the expired gas [11,12]. This release causes an increase in the measured ETCO 2 , which can roughly indicate the CO 2 blood level.…”

Section: Discussionmentioning

confidence: 99%

Correlation of CO2 pneumoperitoneal pressures between rodents and humans

et al. 2008

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The neglected increase in ETCO(2) in pressures > or =8 mmHg, in the rat correlates to high pressures in humans (above 14-20 mmHg) when CO(2) diffusion through the peritoneum declines due to pressure occlusion of peritoneal capillaries. The maximal ventilatory pressures generated in the rat in intra-abdominal pressures > or =8 mmHg correlate to pressures, which are higher than the standard working pressures in humans. Thus, pneumoperitoneal pressures >8 mmHg in the rat do not simulate routine working pressures employed in humans. A pressure of 5 mmHg is optimal in a rat model to simulate laparoscopy in humans.

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“…16 A clear understanding of the physiology of the pneumoperitoneum is important to avoid the significant percentage of complications that are a direct result of these alterations. A multi-institutional review of 185 patients undergoing laparoscopic nephrectomy revealed that 35% of the 34 reported complications were a direct result of the physiologic changes attributable to laparoscopy.…”

Section: Physiologic Complicationsmentioning

confidence: 99%

Complications of Hand-Assisted Laparoscopic Urologic Surgery

Hedican

2004

Journal of Endourology

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Since the first urologic case was reported in 1997, hand-assisted laparoscopic surgery (HALS) has proven to be useful for both the experienced and the inexperienced laparoscopic surgeon. In a recent series of 196 cases at three major medical institutions, 18 patients (9.2%) suffered 32 major complications, and 28 patients (14.3%) had 31 minor complications. The most common major complications were small-bowel injury, requirement for open conversion to control bleeding, and need for reintubation. The most frequent minor complications were urinary retention, splenic capsular injury, and prolonged ileus. The author discusses ways of recognizing and managing the complications of HALS, including physiologic, access-related, intraoperative, and post-operative problems.

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Pathophysiologic effects of prolonged laparoscopic operation

Cited by 25 publications

References 77 publications

Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective study

Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic submucosal dissection of early colorectal neoplasia with carbon dioxide insufflation: a prospective study

Correlation of CO2 pneumoperitoneal pressures between rodents and humans

Complications of Hand-Assisted Laparoscopic Urologic Surgery

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