Pathology of Mediterranean Lymphoma

Al‐Saleem, Tahseen; Zardawi, I. M.

doi:10.1016/s0140-6736(78)90896-6

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…This is difficult, so in earlier series only 20-70% of IPSID patients [44,48,51] and 30% of lymphoma patients [48] had detectable OE chains in the serum. Using more sensitive techniques and looking at jejunal juice and intestinal plasma cells, Rambaud [3] found y chains in every patient with IPSID studied.…”

Section: Detection Of Ol Chainsmentioning

confidence: 98%

“…The spectrum ranges from benign plasma cell proliferation with a-chain (immunoglobulin heavy chain) production (a-chain disease) to malignant lymphoma. Not every case of lymphoma has detectable a chains, but the epidemiology of the lymphoma and of a-chain disease is the same [3] and progression from a-chain disease to lymphoma is described [44], suggesting that they are part of the saine disorder. The lymphoma bas been given many names--Mediterranean lymphoma, Middle East lymphoma, primary upper small intestinal lymphoma (PUSIL), lymphoma of y disease-but perhaps lymphoma of IPS1D is most satisfactory.…”

Section: Lymphoma Of Immunoproliferative Small Intestinal Disease (Me...mentioning

confidence: 99%

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Small intestinal lymphoma

Cooper

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1985

World j. surg.

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This paper reviews small intestinal lymphoma. Although a major emphasis is placed on primary small intestinal lymphoma of the “Western” type, the important topic of lymphoma in celiac disease is discussed. Our own recent experience of 7 patients with lymphoma in celiac disease is presented. The lymphoma of immunoproliferative small intestinal disease (“Mediterranean” lymphoma) and the associated α‐chain disease are also reviewed, with emphasis on the differences from the “Western” type of primary small intestinal lymphoma.

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Section: Detection Of Ol Chainsmentioning

confidence: 98%

Section: Lymphoma Of Immunoproliferative Small Intestinal Disease (Me...mentioning

confidence: 99%

Small intestinal lymphoma

Cooper

Read

1985

World j. surg.

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Evidence of Acquired Immune Deficiencies in Mediterranean Lymphoma

Al-Saleem

1978

The Lancet

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Primary lymphomas of the small intestine in Iraq: a pathological study of 145 cases

Al‐Saleem

Zardawi

1979

Histopathology

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The histopathology of 145 malignant lymphomas of the small intestine in Iraq have been studied and results compared with the clinical and immunological findings. The most common pathology was an intense mucosal lymphoplasmacytic proliferation effacing the villi and crypts partially or completely. This was either 'pure', usually of mature plasma cells limited to the lamina propria or associated with a fullblown lymphoplasmacytic lymphoma, almost always of the upper small intestine. The syndrome presented as abdominal pain, chronic diarrhoea, clubbing and, sometimes, the serological demonstration of alpha heavy chains. Other types of lymphomas were associated with 'non-specific' mucosal inflammation or follicular lymphoid hyperplasia. They were either lymphocytic, plasmacytic or lymphoblastic with 'starry sky' histiocytic reaction, representing distinct clinicopathological entities unrelated to 'alpha heavy chain disease'. Hodgkin's disease was extremely rare in this series.

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Pathology of Mediterranean Lymphoma

Cited by 4 publications

References 6 publications

Small intestinal lymphoma

Small intestinal lymphoma

Evidence of Acquired Immune Deficiencies in Mediterranean Lymphoma

Primary lymphomas of the small intestine in Iraq: a pathological study of 145 cases

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