Pathology of cyclodiode laser: a series of nine enucleated eyes

Diode laser transcleral cyclophotocoagulation for refractory glaucoma: a 1 year follow-up of patients treated using an aggressive protocol

“…Our choice of this setting is based on studies of human cadaver eyes, where the higher end of optimum energy for DCPC was found to be 3-4.5 J per laser spot, 19 as well as on histopathologic examination of treated eyes. 20,21 Secondly, this higher power setting has already proved to be safe when used previously in retreating cases that were not controlled with the initial 1500 mW treatment. 1 23 26 18 14 17 19 12 1 24 26 30 38 20 16 13 2 25 34 21 9 10 2 13 1 26 50 32 34 30 35 11 2 27 42 28 32 30 36 11 1 28 44 24 26 28 32 12 1 29 33 7 10 8 10 11 1 30 49 26 30 34 46 12 2 31 55 30 38 18 14 13 2 32 32 14 10 17 22 12 1 33 26 19 20 19 20 12 1 34 40 18 18 17 18 11 1 35 50 30 26 19 16 13 2 36 35 18 20 16 21 …”

Cyclodestructive Procedures

“…36 This study examines histological outcomes in nine cases in humans, and correlates this with the clinical c course in each eye. 28 Repeated use of the G-probe in transscleral cyclophotocoagulation, with ethylene oxide sterilization in between, resulted in an average decrease of 3% in laser energy delivered per repeated cycle of use up to the fourth cycle. No signs of physical damage were found.…”

“…Ciliary processes are, however, frequently spared within the treatment zone and may account for early or late treatment failure. [22][23][24] Histopathological studies of enucleation specimens following laser cyclophotocoagulation (Diode and Nd:YAG laser) and cyclocryotherapy have been performed in humans [25][26][27][28][29] and animals. 12,[30][31][32][33][34][35] We have previously reported histopathology of two cases of clinical failure following Diode laser cyclophotocoagulation.…”

32 Cyclodestructive Procedures

“…No signs of physical damage were found. [25][26][27][28] Laser G-probes remain functional after repeated use and ethylene oxide resterilization for up to four cycles. No visible physical damage to the probes was identified.…”