Pathologische Mitbewegungen nach Schlaganfall: I. Epidemiologie

Bachteler, S.; Andrés, Francisco Javier Sanjuán; Gerloff, C.

doi:10.1055/s-2003-816409

Cited by 1 publication

(1 citation statement)

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“…As little is known about the sensitivity of CMC analysis, we cannot rule out that small populations of neurons in the contralesional M1 are also subliminally coupled with muscle activity in the paretic hand. This is especially suggested by the occasional observation of associated movements after stroke (Rijntjes et al ., 1999; Bachteler et al ., 2003). Whether these associated movements are the consequence of incompletely separated motor control of both hands by contralesional M1 or whether it reflects bilateral coupling of motor action on a higher level of motor processing cannot be disentangled easily (Weiller et al ., 1993; Wittenberg et al ., 2000).…”

Section: Discussionmentioning

confidence: 99%

Crossed cortico‐spinal motor control after capsular stroke

Braun

Staudt

Schmitt

et al. 2007

Eur J of Neuroscience

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While it is widely accepted that multiple nonprimary motor areas such as the dorsal premotor cortex contribute to recovery from stroke, the contribution of the ipsilesional and contralesional primary motor cortex (M1) is controversial. It has been suggested that re-instating 'near normal' activation patterns is a good strategy for recovery of function [Baron et al., (2004) Cerebrovasc. Dis., 18, 260-267; Ward & Cohen, (2004) Arch. Neurol., 61, 1844-1848]. The present study addressed this aspect of stroke recovery by combining transcranial magnetic stimulation (TMS) and magnetoencephalography (MEG) in a cross-sectional design on nine patients with well-recovered motor function 17.6 +/- 5.5 months (mean +/- SD) after subcortical stroke. While TMS was applied to probe the integrity of the cortico-spinal tract (CST) at rest, MEG was used to test for recruitment of CST pathways during a motor challenge [cortico-muscular coherence (CMC) in a precision grip task]. With both techniques, crossed cortico-spinal connectivity could be demonstrated. A significant correlation (r = 0.85) of CMC magnitude and recovered muscle strength underlined the functional relevance of crossed CST integrity for successful recovery. In conclusion, at the descriptive level, crossed CST connectivity is a common finding in well-recovered patients with capsular stroke. This renders it likely that maintaining or regaining use of crossed CST fibers is one way to achieve effective recovery.

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Section: Discussionmentioning

confidence: 99%