Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis

Singhabahu, Rachitha; Gamage, Sujani Madhurika Kodagoda; Gopalan, Vinod

doi:10.1016/j.cpt.2023.04.001

Cancer Pathogenesis and Therapy

2024

DOI: 10.1016/j.cpt.2023.04.001

|View full text |Cite

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis

Rachitha Singhabahu¹,

Sujani Madhurika Kodagoda Gamage²,

Vinod Gopalan³

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 71 publications

(198 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

Consoli,

Sorrenti,

Gulisano

et al. 2024

Mol Cell Biochem

View full text Add to dashboard Cite

Breast cancer remains a significant global health challenge, with diverse subtypes and complex molecular mechanisms underlying its development and progression. This review comprehensively examines recent advances in breast cancer research, with a focus on classification, molecular pathways, and the role of heme oxygenases (HO), heme metabolism implications, and therapeutic innovations. The classification of breast cancer subtypes based on molecular profiling has significantly improved diagnosis and treatment strategies, allowing for tailored approaches to patient care. Molecular studies have elucidated key signaling pathways and biomarkers implicated in breast cancer pathogenesis, shedding light on potential targets for therapeutic intervention. Notably, emerging evidence suggests a critical role for heme oxygenases, particularly HO-1, in breast cancer progression and therapeutic resistance, highlighting the importance of understanding heme metabolism in cancer biology. Furthermore, this review highlights recent advances in breast cancer therapy, including targeted therapies, immunotherapy, and novel drug delivery systems. Understanding the complex interplay between breast cancer subtypes, molecular pathways, and innovative therapeutic approaches is essential for improving patient outcomes and developing more effective treatment strategies in the fight against breast cancer.

show abstract

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

Consoli,

Sorrenti,

Gulisano

et al. 2024

Mol Cell Biochem

View full text Add to dashboard Cite

show abstract

Proteomic and metabolomic analysis of ageing beef exudate to determine that iron metabolism enhances muscle protein and lipid oxidation

Liu,

Pan,

Yue

et al. 2023

Food Chemistry: X

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis

Cited by 2 publications

References 71 publications

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

Proteomic and metabolomic analysis of ageing beef exudate to determine that iron metabolism enhances muscle protein and lipid oxidation

Contact Info

Product

Resources

About