Pathological eye movements influence on the recordings of ocular vestibular-evoked myogenic potential

Clinical Neurophysiology Practice

et al. 2019

207

208

Section: How To Record Ovempsmentioning

confidence: 99%

Vestibular evoked myogenic potentials in practice: Methods, pitfalls and clinical applications

Rosengren

Colebatch

Clinical Neurophysiology Practice

et al. 2019

207

208

“…However, oVEMPs were successfully recorded on the third day after treatment, and opsoclonus was eliminated 1 month after treatment. Thus, absent oVEMP in patients with acute opsoclonus owing to recording failure rather than underlying pathology further supports treatment efficacy for attenuating the opsoclonus . Restated, monitoring the oVEMP responses provides a novel tool to evaluate the treatment outcome in patients with pathologic eye movements (ie, opsoclonus).…”

mentioning

confidence: 90%

“…Alternatively, therapeutic diagnosis using corticosteroids and adrenocorticotropic hormone has been described as the gold standard . After 3-day treatment by corticosteroid and clonazepam, declining intensity and frequency of opsoclonus was identified, as evidenced by the recently developed ocular vestibulo-evoked myogenic potential (oVEMP) test, which has been reported elsewhere . Briefly, we add this information.…”

mentioning

confidence: 98%

Opsoclonus-Myoclonus Syndrome—Reply

Hsu

JAMA Otolaryngol Head Neck Surg

2018

Self Cite

inadequate; rather, it indicated that the cutoff of 24 could best differentiate the patient survival in the data set.On the contrary, the study by Kuo et al 3 performed multiple multivariable analyses to determine the lymph node count cutoff, based on the survival decrease in successive groups compared with the count associated with the best survival. It was unclear how 5 lymph nodes were chosen for nodal grouping and categorization. The authors eventually picked 16 or more as the cutoff, where all groups under this value were significantly different from the reference group. The method used here did not account for multiple comparisons. In addition, the reason for choosing the reference group based on the lowest hazard was unclear, it implied that patients in the reference group had the best outcome and therefore perhaps the lymph node count of the reference group should be used as the threshold value.We do agree with the comments made by Dr Judson stating that, when using lymph node yield as a quality metric, it is crucial to employ the appropriate analysis to determine the actual threshold. It is perhaps more important to recognize that the association observed here and in other studies does not imply causation. Although attempts can be made to generate a practice guideline for lymph node dissection, other clinical and patient factors should also remain the key drivers for estimating patient prognosis. 4

“…The oVEMP test evaluates the vestibulo‐ocular reflex (VOR) via the superior vestibular nerve, while the cVEMP test assesses the ipsilateral sacculo‐collic reflex, via the inferior vestibular nerve. As both oVEMP and cVEMP tests are unrelated to the eye movements, they are applicable to congenital nystagmus patients. This study adopted an inner ear test battery and oculomotor function test by electronystagmography (ENG) to investigate how congenital nystagmus confounds the oculomotor function test and proposes an inner ear test battery to resolve the potential pitfalls.…”

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confidence: 99%

Comorbid inner ear disorders in 50 patients with congenital nystagmus

Huang

Hsu

Clinical Otolaryngology

2018