Pathological Crying Caused by High-Frequency Stimulation in the Region of the Caudal Internal Capsule

Low, Hu Liang; Sayer, Faisal T.; Honey, Christopher R.

doi:10.1001/archneurol.2007.53

Cited by 23 publications

(18 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Pseudobulbar laughter and crying (mood incongruent) have been reported with stimulation, and both have been reportedly addressed by the use of antidepressant medications and by DBS reprogramming [55–57]. Two of the most worrisome stimulation-induced issues are depression and mania [32,58–62].…”

Section: Stimulation-related Urgencies/emergenciesmentioning

confidence: 99%

Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies

Morishita

Foote

Burdick

et al. 2010

Parkinsonism & Related Disorders

View full text Add to dashboard Cite

Deep brain stimulation (DBS) has been increasingly utilized for the therapeutic treatment of movement disorders, and with the advent of this therapy more postoperative urgencies and emergencies have emerged. In this paper, we will review, identify, and suggest management strategies for both intra-and postoperative urgencies and emergencies. We have separated the scenarios into 1-surgery/procedure related, 2-hardware related, 3-stimulation induced difficulties, and 4-others. We have included ten illustrative (and actual) case vignettes to augment the discussion of each issue.

show abstract

Section: Stimulation-related Urgencies/emergenciesmentioning

confidence: 99%

Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies

Morishita

Foote

Burdick

et al. 2010

Parkinsonism & Related Disorders

View full text Add to dashboard Cite

show abstract

“…102 Stimulation resulted in pathologic crying. This effect was observed during her postoperative evaluation.…”

Section: Dbs and Imaging: Understanding Dbs Mechanisms And The Human mentioning

confidence: 99%

Neuroimaging and Deep Brain Stimulation

Dormont¹,

Seidenwurm²,

Galanaud³

et al. 2009

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

SUMMARY: Deep brain stimulation (DBS) is a new neurosurgical method principally used for the treatment of Parkinson disease (PD).Many new applications of DBS are under development, including the treatment of intractable psychiatric diseases. Brain imaging is used for the selection of patients for DBS, to localize the target nucleus, to detect complications, and to evaluate the final electrode contact position. In patients with implanted DBS systems, there is a risk of electrode heating when MR imaging is performed. This contraindicates MR imaging unless specific precautions are taken. Involvement of neuroradiologists in DBS procedures is essential to optimize presurgical evaluation, targeting, and postoperative anatomic results. The precision of the neuroradiologic correlation with anatomic data and clinical outcomes in DBS promises to yield significant basic science and clinical advances in the future. Chronic high-frequency stimulation of the ventral intermediate nucleus (VIM) of the thalamus was first described in the early 1990s by Benabid et al.1 These authors implanted chronic stimulating electrodes in the VIM connected to a subcutaneous pulse generator positioned in the thoracic region to treat disabling tremor in 26 patients with Parkinson disease (PD) and in 6 with essential tremor.1 They demonstrated the effectiveness of this technique and its ability to produce complete relief from tremor. Improvement was maintained for up to 29 months. This was the first clinical demonstration that chronic high-frequency stimulation of nuclei (deep brain stimulation [DBS]) could replace destructive lesion-producing functional neurosurgery such as thalamotomy. This new technique was reversible and led to a renaissance in functional neurosurgery.Next, the same team introduced bilateral DBS of the subthalamic nucleus (STN) in patients with disabling akineticrigid PD and severe motor fluctuations.2 This work extended data obtained in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine monkey model of PD showing that lesions and electric stimulation of the subthalamic nucleus reduced all of the major motor disturbances in this animal model. The results in patients with advanced PD were striking and were reproduced in many centers internationally. The US Food and Drug Administration approved the use of DBS for treatment of advanced PD with bilateral STN stimulation in 2002 and internal globus pallidus (GPi) stimulation in 2003. The main indication for DBS remains advanced PD, but numerous additional applications have been developed, ranging from dystonia to cluster headache, Tourette syndrome, and even psychiatric indications like obsessive-compulsive disorders (OCD) and major depression.DBS is a neurosurgical method, but the role of neuroimaging in successful DBS intervention is critical. Neuroimaging is used for the preoperative selection of patients who will have DBS and to localize the intended target nuclei. In the postoperative period, imaging detects complications that uncommonly accompany the procedure, confirms the pos...

show abstract

“…Previous isolated pre-and post-DBS reports have revealed smatterings of the seven historical symptoms focused in this current study (8,10,11,14,(20)(21)(22)(23)(24). The available reports revealed a time association to DBS implantation.…”

Section: Discussionmentioning

confidence: 60%

Taking a Better History for Behavioral Issues Pre- and Post-Deep Brain Stimulation: Issues Missed by Standardized Scales

Bernal-Pacheco

Oyama

Foote

et al. 2013

Neuromodulation: Technology at the Neural Interface

View full text Add to dashboard Cite

Pathological Crying Caused by High-Frequency Stimulation in the Region of the Caudal Internal Capsule

Abstract: Background: Pathological crying has been rarely reported after deep brain stimulation. The exact neural substrate is unknown, but it is often assumed that pathological crying and the pseudobulbar syndrome result from disturbances of a common neural pathway.

Cited by 23 publications

References 15 publications

Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies

Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies

Neuroimaging and Deep Brain Stimulation

Taking a Better History for Behavioral Issues Pre- and Post-Deep Brain Stimulation: Issues Missed by Standardized Scales

Contact Info

Product

Resources

About