Pathological changes caused by Anoplocephala perfoliata in the mucosa/submucosa and in the enteric nervous system of equine ileocecal junction

Comparison of the sensitivity of coprological methods in detecting Anoplocephala perfoliata invasions

“…Mucosal ulceration, submucosal oedema, hypertrophy of the distal ileum, and decreased ileocaecal valve distensibility have all been reported to occur at the site of parasite attachment, and the severity of pathology is directly proportional to parasite infection intensity (Pavone et al 2011; De Almeida et al 2008). The mechanisms by which this pathology arises remain unexplored, but it would seem reasonable to consider both mechanical obstruction and parasite-derived antigens in these processes.…”

“…Its prevalence varies between 6 and 100 % (Trotz-Williams et al 2008; Michela et al 2009; Sangioni et al 2009; Pavone et al 2011; Hinney et al 2011) In Poland, its prevalence varies from 0 to even 72 % depending on type of breeding system and geographical region (Ślivińska et al 2009; Tomczuk 2012). …”

Caecal intussusceptions and typhlocolitis in horses with severeGastrodiscus aegyptiacusinfestation

“…An association between the severity of intestinal pathology and number of parasites present has been demonstrated for A. perfoliata and cyathostomin species (Murphy and Love ; Pavone et al . ). In this series, all cases subject to necropsy examination had heavy G. aegyptiacus burdens (individual parasite counts were not performed) as demonstrated in Fig .…”

“…Myenteric ganglionitis has been suggested as a specific mechanism for compromised motility in parasitic infestations (Pavone et al . ). Typhlocolitis has been reported both on its own and in conjunction with caecal intussusception (Mair et al .…”

“…Parasites including Anoplocephala perfoliata (A. perfoliata) and cyathostomin species have been seen in conjunction with caecal intussusception and published case series suggest their possible association (Barclay et al 1982;Mair et al 2000). Myenteric ganglionitis has been suggested as a specific mechanism for compromised motility in parasitic infestations (Pavone et al 2011). Typhlocolitis has been reported both on its own and in conjunction with caecal intussusception (Mair et al 2000;Smith et al 2015).…”