Pathological Case of the Month

Abstract

PREVIOUSLY healthy female infant developed vomiting, lethargy, poor oral intake, gray coloring, and decreased lower extremity movement at age 8 weeks. Respiratory acidosis prompted intubation. An electromyogram (EMG) showed disorganized muscle fibrillations consistent with inflammatory myopathy. Trials of intravenous immunoglobulin and methotrexate proved ineffective. Muscle weakness and stiffness pro