Pathological calcification in canine tendon-derived cells is modulated by extracellular ATP
Danae E. Zamboulis,
Neil Marr,
Alaa Moustafa
et al.
Abstract:Tendon calcification is a commonly associated with degenerative tendinopathy of the Achilles tendons in dogs. It is characterised by the formation of calcific deposits and is refractory to treatment, often re-forming after surgical removal. Little is known about its pathogenesis and therefore the aims of this study were to develop an in vitro model of canine tendon calcification and use this model to investigate mechanisms driving calcification. Cells from the canine Achilles tendon were cultured with differen… Show more
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