Pathological and Serobiochemical Studies on Naturally Occurring Kidney Affections in Camels (<i>Camelus dromedarius</i>)

Barakat, S.E.M.; Al-Hizab, F. A.; Moqbel,

doi:10.5958/2277-8934.2017.00008.x

Cited by 5 publications

(9 citation statements)

References 4 publications

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“…However, Ismail et al (11) found significantly higher urea concentrations in goats with subclinical PT when compared with animals in the control group, due to the mobilization of proteins that occurs at the end of pregnancy. The findings of Barakat et al (23) and Souto et al (16) support this observation, as they attributed the increase in serum urea levels in clinical PT in goats to fatty infiltration in the tubular epithelium of the kidneys. This infiltration leads to azotemia, which is associated with a decrease in glomerular filtration rate and a consequent reduction in the urinary excretion of this compound.…”

Section: Protein Profilementioning

confidence: 77%

Protein, enzymatic and mineral indicators of clinical and subclinical pregnancy toxemia during the transitional period in dairy goats

Souto,

Soares,

Macedo

et al. 2023

Ciênc. anim. bras.

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The purpose of this study was to evaluate the influence of clinical and subclinical pregnancy toxemia (PT) forms on the dynamics of blood metabolites, composing the protein, enzymatic and mineral profiles of dairy goats during the transitional period. 111 multiparous dairy goats were used in this research. The animals were raised under an intensive system. Experimental groups (n=3) were created using the βHB blood concentrations as a cut-off point. The G1 or control group (n = 40), G2 or subclinical PT group (n = 39) were established when least one of the experimental assessment times presented βHB values between 0.8 mmol/L and 1.6 mmol/L; whereas G3 or clinical PT group (n = 32), which at any of the experimental assessment times of βHB values were higher than 1.6 mmol / L when verified and also presented clinical signs of PT. The animals were evaluated on the 30th , 20th and 10th day ante-partum (dap), at parturition and on the 10th, 20th and 30th day postpartum (dpp). Total proteins (TP), albumin, globulin, urea, creatinine, aspartate aminotransferase (AST), Gamma glutamiltransferase (GGT), creatine kinase (CK), amylase, phosphorus, chloride and calcium, sodium and potassium ions were measured. The analysis of variance (F Test) was performed in order to investigate the effects and interactions between group and assessment times. Clinical and/or subclinical disease during the transitional period resulted in an increase of phosphorus and potassium concentrations (P<0.05), while a decrease in total protein, albumin, globulin, and ionized calcium values was observed (P<0.05). No statistical effect of PT on urea, creatinine, AST, GGT, CK, amylase and sodium was observed (P>0.05). Except the ionized calcium and phosphorus, the levels of all the metabolites were influenced (P<0.05) by late pregnancy, parturition and lactation. The occurrence of the subclinical form was higher than the clinical form during the transitional period. Among the all variables studied, mineral profile were those that suffered alteration resulting from PT, highlighting the ionized calcium. Attention is drawn to the magnitude of the impact of disease on these components interfering in animal health.

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Section: Protein Profilementioning

confidence: 77%

Protein, enzymatic and mineral indicators of clinical and subclinical pregnancy toxemia during the transitional period in dairy goats

Souto,

Soares,

Macedo

et al. 2023

Ciênc. anim. bras.

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“…No entanto, Ismail et al (11) encontraram concentrações de ureia significativamente mais altas em cabras com TP na forma subclínica quando comparadas com animais do grupo controle, em virtude da mobilização de proteínas que ocorre no final da gestação. Assim como dos achados de Barakat et al (23) e de Souto et al (16) que atribuíram a elevação nos níveis séricos de ureia na TP clínica em cabras à infiltração gordurosa no epitélio tubular dos rins levando a um quadro de azotemia, relacionado a uma diminuição da taxa de filtração glomerular e consequente redução na excreção urinária desse composto.…”

Section: Perfil Proteicounclassified

“…Esse comportamento da CK, concomitante à AST demonstra que a TP na sua forma clínica ou subclínica não desencadeou lesão muscular nas cabras empregadas neste estudo, especialmente, pela manifestação em média mais branda da forma clínica, como indicado pelos valores médios de ßHB. No entanto, em estudo realizado por Barakat et al (23) e Santos (28) a CK encontrou-se significativamente aumentada em cabras e ovelhas com TP clínica.…”

Section: Perfil Enzimáticounclassified

Indicadores proteicos, enzimáticos e minerais da toxemia da prenhez clínica e subclínica durante o período de transição de cabras leiteiras

Souto,

Soares,

Macedo

et al. 2023

Ciênc. anim. bras.

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Resumo O objetivo deste estudo foi avaliar a influência das formas clínica e subclínica da toxemia da prenhez (TP) na dinâmica dos metabólitos sanguíneos, compondo os perfis proteico, enzimático e mineral das cabras leiteiras durante o período de transição. Foram utilizadas 111 cabras multíparas que eram criadas em sistema intensivo. Grupos experimentais (n=3) foram criados utilizando diferentes concentrações séricas de βHB como ponto de corte, o G1 grupo controle (n=40), G2 grupo subclínico da TP (n=39) estabelecido quando pelo menos um dos momentos experimentais apresentou valores de βHB entre 0,8 mmol/L e 1,6 mmol/L; e o grupo G3, com manifestação clínica da TP (n=32), que em qualquer um dos momentos os valores de βHB foram superiores a 1,6 mmol/L. Os animais foram avaliados aos 30º, 20º e 10º dias antes do parto (dap), no parto e no 10º, 20º e 30º dia pós-parto (dpp). Proteínas totais (PT), albumina, globulina, ureia, creatinina, aspartato aminotransferase (AST), gama glutamiltransferase (GGT), creatina quinase (CK), amilase, fósforo, cloreto e cálcio, sódio e potássio foram mensurados. A análise de variância (Teste F) foi realizada com o objetivo de investigar os efeitos e interações entre os tempos dos grupos. A doença clínica e/ou subclínica resultou num aumento das concentrações de fósforo e potássio (P<0,05), foi observada uma diminuição nos valores de proteína total, albumina, globulina e cálcio ionizado (P<0,05). Não houve efeito estatístico da TP sobre a uréia, creatinina, AST, GGT, CK, amilase e sódio (P>0,05). A ocorrência da forma subclínica foi maior que a clínica durante o período de transição. As variáveis que compõem o perfil mineral foram as que apresentaram alterações decorrentes da TP, destacando-se, o cálcio ionizado. Chama-se a atenção o impacto que a doença reflete nesses componentes e na saúde do animal.

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“…Lesions included congestion, hemorrhage, hydronephrosis, acute glomerulonephritis, subacute glomerulonephritis, chronic glomerulonephritis, diffuse interstitial nephritis, focal interstitial nephritis, renal cyst, hyaline degeneration, renal amyloidosis, tubular nephrosis, pyelonephritis, hemosiderosis, and renal toxicity [ 2 ]. In a third study conducted in Al-Ahsa abattoir, Saudi Arabia, gross and microscopic lesions of the kidney were investigated in 50 adult camels [ 3 ]. Of the camels, 33 (66%) had gross kidney lesions, whereas 17 (34%) were found apparently healthy.…”

Section: Introductionmentioning

confidence: 99%

“…Renal lesions included hydronephrosis, renal hemorrhages, and renal necrosis. In the camels with renal lesions, microscopic changes included glomerular shrinkage and hyalinization, proteinaceous casts, cortical and medullary congestion, tubular cell swelling, interstitial hemorrhage, and thickening of the glomerular tufts [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrasonography of the Kidneys in Healthy and Diseased Camels (Camelus dromedarius)

Tadjine

2020

Veterinary Medicine International

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This review article is written to describe the results of ultrasonography of the kidneys in healthy camels as well as camels with some renal disorders. In the dromedary camel, the physiology of the kidney is of interest in view of the specialization of the camel to hot dry deserts and to prolonged periods without water. It plays an important role in water conservation through the production of highly concentrated urine that may predispose animal to varieties of renal disorders. Examples of kidney affections in dromedary camels are renal capsular pigmentation, medullary hyperemia, subcapsular calcification, cortical and medullar discoloration, hemorrhage in renal pelvis, nephrolithiasis, and hydatidosis. Congestion, hemorrhage, hydronephrosis, acute glomerulonephritis, subacute glomerulonephritis, chronic glomerulonephritis, diffuse interstitial nephritis, focal interstitial nephritis, renal cyst, hyaline degeneration, renal amyloidosis, tubular nephrosis, pyelonephritis, hemosiderosis, and renal toxicity. When the kidney is examined by ultrasonography, the clinician can get sufficient information about the size, position, and echo patterns of the renal cortex and medulla and renal pelvis and outlines of the renal blood vessels. In recent years, ultrasonography has been used in camels for scanning of the healthy status as well as evaluation and determining the diagnosis and prognosis of diseased cases. Examples of diseases evaluated by ultrasonography are paratuberculosis, trypanosomiasis, pneumonia, pleurisy, gastrointestinal neoplasms, chronic peritonitis, splenic abscessation, and hepatic disorders. Of the renal disorders assessed by ultrasonography are nephrolithiasis, hydronephrosis, pyelonephritis, renal abscessation, and renal neoplasms. Ultrasound guidance in biopsy of renal specimens has also been reported in dromedary camels.

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Pathological and Serobiochemical Studies on Naturally Occurring Kidney Affections in Camels (Camelus dromedarius)

Cited by 5 publications

References 4 publications

Protein, enzymatic and mineral indicators of clinical and subclinical pregnancy toxemia during the transitional period in dairy goats

Protein, enzymatic and mineral indicators of clinical and subclinical pregnancy toxemia during the transitional period in dairy goats

Indicadores proteicos, enzimáticos e minerais da toxemia da prenhez clínica e subclínica durante o período de transição de cabras leiteiras

Ultrasonography of the Kidneys in Healthy and Diseased Camels (Camelus dromedarius)

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