Pathologic Significance of Nephromegaly in Pediatric Disease

Brenbridge, AN

doi:10.1001/archpedi.1987.04460060068036

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“…Our data support the theory that compensatory renal growth is consistent with sufficient renal function 27 28. The detection of abnormal kidney growth did indeed, in combination with screening for additional parenchymal abnormalities, uncover all patients with CKD stage III and worse in our study (table 1).…”

Section: Discussionsupporting

confidence: 88%

Sonographic long-term study: paediatric growth charts for single kidneys

Spira

Jacobi

Frankenschmidt

et al. 2009

Archives of Disease in Childhood

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Section: Discussionsupporting

confidence: 88%

Sonographic long-term study: paediatric growth charts for single kidneys

Spira

Jacobi

Frankenschmidt

et al. 2009

Archives of Disease in Childhood

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Prognostic value of sonography in childhood nephrotic syndrome

et al. 1994

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This retrospective case review of 43 children with primary nephrotic syndrome was designed to evaluate the relationship among renal ultrasound findings at presentation, subsequent corticosteroid responsiveness and histological diagnoses. Fifty-one percent of patients had abnormal sonograms; nephromegaly was present in 42% and increased renal echogenicity in 35%. There was no relationship between nephromegaly and either response to corticosteroids or specific glomerular lesions causing nephrosis. Although the presence of echogenic kidneys did not denote a particular type of renal disease, it was significantly more frequent in corticosteroid-resistant than in corticosteroid-responsive patients (62% vs. 18%, P < 0.05). We conclude that increased renal echogenicity at time of presentation is a possible indicator of corticosteroid resistance in children with primary nephrotic syndrome.

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Pathologic Significance of Nephromegaly in Pediatric Disease

Cited by 2 publications

References 13 publications

Sonographic long-term study: paediatric growth charts for single kidneys

Sonographic long-term study: paediatric growth charts for single kidneys

Prognostic value of sonography in childhood nephrotic syndrome

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