Pathologic Rupture of the Spleen in Non-Hodgkin's Lymphoma

Andrews, D. F.; Hernandez, Robert; Grafton, Warren D.; Williams, Darryl M.

doi:10.1001/archinte.1980.00330130121029

Cited by 22 publications

(7 citation statements)

References 4 publications

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“…Several cases of splenic rupture with non-Hodgkin's lymphoma have been reported [1,4,6,9], but, according to our knowledge, only one previous case is known to be associated with MCL [8].…”

Section: Discussionmentioning

confidence: 83%

Spontaneous splenic rupture in two patients with a blastoid variant of mantle cell lymphoma

Oinonen

Franssila

Elonen

1997

Annals of Hematology

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Spontaneous rupture of the spleen is a rare complication of hematological malignancies, occurring most commonly in patients with acute leukemia, but it has been documented in chronic leukemias and also in lymphomas. We report two patients with histologically and immunohistochemically confirmed mantle cell lymphoma (MCL) who experienced a spontaneous splenic rupture. An 80-year-old woman and a 51-year-old man had a blastoid variant of MCL and responded poorly to conventional treatment. Both patients recovered after splenectomy. The woman died of progressive lymphoma 2 months later. An allogeneic bone marrow transplantation was performed in the man with a good initial result, but an aggressive relapse was seen only 6 months later and he died of progressive lymphoma. In view of our data, we suggest special caution when MCL is complicated by rapid progression and severe splenomegaly. Although it is a rare phenomenon, the risk of splenic rupture should be kept in mind.

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“…Several cases of splenic rupture with non-Hodgkin's lymphoma have been reported [1,4,6,9], but, according to our knowledge, only one previous case is known to be associated with MCL [8].…”

Section: Discussionmentioning

confidence: 83%

Spontaneous splenic rupture in two patients with a blastoid variant of mantle cell lymphoma

Oinonen

Franssila

Elonen

1997

Annals of Hematology

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“…Small cysts are usually asymptomatic and are found incidentally by imaging techniques. Less often, there is splenomegaly and/or hepatomegaly, lymphadenopathy, abdominal distension, nausea, and vomiting [4][5][6][7][8][9][10][30][31][32][33]. These cysts do not require any further treatment unless the wall is very thin and in danger of rupture.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Rupture of a True Splenic Cyst Diagnosed by Laparoscopy

Karasakalides¹,

Ganas²,

Triantafillidou³

et al. 2006

Dig Dis Sci

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“…Focal lesions of the spleen (i. e. metastasis, infiltrating lymphoma cells, hamartoma, haemangioma, infarction) are associated with complications, especially splenic ruptures [15,16]. Among patients with malignant diseases and evidence of spontaneous splenic rupture, splenic infarctions have been demonstrated to be responsible for the splenic rupture in about 50 % of the cases [17].…”

Section: Discussionmentioning

confidence: 99%