Pathologic Quiz Case: Testicular Pain and Scrotal Swelling in a 25-Year-Old Man

Large Cell Calcifying Sertoli Cell Tumor

“…The LCCSCT, one of the rarest sex cord-stromal tumors of the testis, was initially described by Lange et al6 in 1960 and then formally introduced as a distinct entity by Proppe and Scully in 1980 5. To date, 45 clinically benign,1,5,9,12,25,27,29–45 53 clinically ambiguous,1,16,27,36,38,43,46–78 and 17 clinically malignant1–3,5,23–28 cases have been reported in the English language literature, including this series, according to our comprehensive review (Tables 2, 3, Supplementary Table 1, Supplemental Digital Content 1, http://links.lww.com/PAS/B288).…”