Pathogenicity of Erysipelothrix rhusiopathiae strains of serovars 1a,3,5,6,8,11,21, and type N isolated from slaughter pigs affected with chronic erysipelas.

Takahashi, Toshio; Sawada, Takuo; Seto, Kenji; Muramatsu, Masatake; Matsumoto, Tsutomu; Kanzaki, Masako

doi:10.1292/jvms1939.47.1

Cited by 19 publications

(12 citation statements)

References 4 publications

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“…The pathogenicity of isolates for mice classified according to origin and serotype was in accordance with previous results [17]. No correlation between pathogenicity and serotype was observed.…”

Section: Discussionsupporting

confidence: 90%

Etiological and Biological Characteristics of Erysipelothrix rhusiopathiae Isolated between 1994 and 2001 from Pigs with Swine Erysipelas in Japan

et al. 2009

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ABSTRACT. We investigated 66 Erysipelothrix rhusiopathiae strains isolated from pigs affected with swine erysipelas in Japan from 1994 to 2001 for serotype, pathogenicity towards mice, protection in vaccinated mice and antimicrobial susceptibility. Most of the isolates (84.8%) were serotype 1 or 2. For the first time, strains belonging to serotype 21 were isolated from cases of septicemia. Fifty isolates (75.8%) were highly virulent, 12 isolates (18.2%) were weakly virulent and 4 isolates were avirulent strains. All the mice vaccinated with the Koganei 65-0.15 vaccine strain survived challenge exposure with 50 highly virulent isolates. Six isolates (9.1%) grew on TPB-T80 agar containing 0.02% of acriflavine, and this was identical to the growth of the vaccine strain. Forty-seven isolates (71.2%) were resistant to oxytetracycline. The number of strains resistant to oxytetracycline among field isolates increased rapidly each year. Tylosinresistant strains were also isolated (6.1%). These results suggest that certain characteristics, particularly antimicrobial susceptibility of E. rhusiopathiae isolates, change yearly in the field. Therefore, further investigation of the characteristics of E. rhusiopathiae field isolates is necessary.

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Section: Discussionsupporting

confidence: 90%

Etiological and Biological Characteristics of Erysipelothrix rhusiopathiae Isolated between 1994 and 2001 from Pigs with Swine Erysipelas in Japan

et al. 2009

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“…Also, in our study, strains resistant to dihydrostreptomycin were most frequently found in the strains from septicaemic cases. E. rhusiopathiae strains of serotype 1a reportedly have most often been isolated from pigs affected with acute septicaemic erysipelas and generally considered to be highly pathogenic for swine (Takahashi et al, 1985). Consequently, it was indicated that strains resistant to dihydrostreptomycin most frequently distribute in the strains belonging to serotype 1a and had high pathogenicity for swine.…”

Section: Discussionmentioning

confidence: 99%

“…At present, strains of E. rhusiopathiae are classi®ed into 22 serotypes and N type (Takahashi et al, 1984a). It has been generally known that most isolates of E. rhusiopathiae from swine erysipelas fall into serotypes 1a, 1b and 2 (Takahashi et al, 1985).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Susceptibilities of Erysipelothrix rhusiopathiae Isolated from Pigs with Swine Erysipelas in Japan, 1988-1998

Yamamoto¹,

Kijima²,

Yoshimura³

et al. 2001

J Vet Med Series B

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The susceptibility to 21 antimicrobial agents of 214 strains of Erysipelothrix rhusiopathiae isolated from pigs affected with swine erysipelas in Japan between 1988 and 1998 was determined. Ampicillin, cloxacillin, benzylpenicillin, ceftiofur, tylosin, enrofloxacin and danofloxacin were the most active agents [minimum inhibitory concentrations (MICs); < or = 0.025-0.78 microgram/ml], followed by cefazolin, virginiamycin, tiamulin, chloramphenicol, florphenicol and oxolinic acid (MICs; 0.1-25 micrograms/ml). Activity was poor or absent with kanamycin and sulfadimethoxine. Strains resistant to dihydrostreptomycin, erythromycin, clindamycin, lincomycin, oxytetracycline and doxycycline were detected. The susceptibilities to dihydrostreptomycin and oxytetracycline tended to decrease. Investigation of the differences in antimicrobial susceptibility of the 214 strains according to their serotypes, sources, isolation years and regions, showed that the strains resistant to dihydrostreptomycin were most frequently found in the strains of serotype 1a and in strains from septicaemic cases. Strains resistant to oxytetracycline were detected in all serotypes and all sources, and most of the strains resistant to erythromycin were detected in the strains of serotype 2. The frequency of strains resistant to dihydrostreptomycin gradually increased from 1988 to 1996, but then decreased between 1997 and 1998. The frequency of strains resistant to oxytetracycline was remained more than 38% from 1988 to 1998. It was suggested that the strains resistant to dihydrostreptomycin and oxytetracycline were distributed over almost all districts of Japan.

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“…Thus, all serovar isolates tested were pathogenic to mice; however, germ‐free piglets inoculated with strains of serovars 5 and 8 survived without clinical symptoms, and the piglets inoculated with the serovar strains did not develop antibodies against E. rhusiopathiae (data not shown). These results are not surprising because E. rhusiopathiae exhibits different pathogenicity between pigs and other hosts, and we also observed that some E. rhusiopathiae serovar 1a strains were pathogenic to pigs but not to mice (unpublished observation).…”

Section: Prevalence (Positive Rate) Of Antibodies Against Erysipelothmentioning

confidence: 99%

Wild boars: A potential source of Erysipelothrix rhusiopathiae infection in Japan

Shimoji

Osaki

Ogawa

et al. 2019

Microbiology and Immunology

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The potential role of wild boars as a source of erysipelas infection was investigated. An ELISA test of wild boar serum samples from 41 prefectures in Japan revealed that proportions of the Erysipelothrix rhusiopathiae‐positive samples were very high in all the prefectures, and the mean positive rate was 95.6% (1312/1372). Serovars of E. rhusiopathiae isolates from wild boars were similar to those of previously reported swine isolates, and all serovar isolates tested were found to be pathogenic to mice. These results suggest that wild boars in Japan constitute a reservoir of E. rhusiopathiae and may pose risks to other animals.

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Pathogenicity of Erysipelothrix rhusiopathiae strains of serovars 1a,3,5,6,8,11,21, and type N isolated from slaughter pigs affected with chronic erysipelas.

Cited by 19 publications

References 4 publications

Etiological and Biological Characteristics of Erysipelothrix rhusiopathiae Isolated between 1994 and 2001 from Pigs with Swine Erysipelas in Japan

Etiological and Biological Characteristics of Erysipelothrix rhusiopathiae Isolated between 1994 and 2001 from Pigs with Swine Erysipelas in Japan

Antimicrobial Susceptibilities of Erysipelothrix rhusiopathiae Isolated from Pigs with Swine Erysipelas in Japan, 1988-1998

Wild boars: A potential source of Erysipelothrix rhusiopathiae infection in Japan

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