Pathogenic diversification of the gut commensalProvidencia alcalifaciensvia acquisition of a second type III secretion system
Jessica A. Klein,
Alexander V. Predeus,
Aimee R. Greissl
et al.
Abstract:Providencia alcalifaciensis a Gram-negative bacterium found in a wide variety of water and land environments and organisms. It has been isolated as part of the gut microbiome of animals and insects, as well as from stool samples of patients with diarrhea. SpecificP. alcalifaciensstrains encode gene homologs of virulence factors found in other pathogenic members of the same Enterobacterales order, such asSalmonella entericaserovar Typhimurium andShigella flexneri.Whether these genes are also pathogenic determin… Show more
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