Pathogenesis, Treatment and Impact on Quality of Life in Psoriasis

Abstract

Background: psoriasis is a papulo-squamous disease with different morphology, severity, distribution and course of disease. The aim of the treatment was to reduce disease activity to a level that permits an acceptable quality of life with negligible toxicity from the treatment itself. About 25% of patients experience major psychological distress due to the disease. Its long duration along with comorbidities have a negative impact on quality of life. Aim of the work: we tried to understand the types, pathogenesis and management of psoriasis, and also try to understand its effect on the quality of life. Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed and EMBASE from January 1994 to March 2017. The following search terms were used: psoriasis, psoriasis classification, psoriasis management, quality of life in psoriasis patients. Aim of the work: we tried to understand the types, pathogenesis, and management of psoriasis, and also try to understand its effect on the quality of life. Conclusion: due to the chronic course, and its noticeable visibility on skin, many patients suffer from major social and psychological ill effects. In majority of the time the health care providers fail to recognize or treat such comorbidities. Healthcare providers must be educated to offer ways to tackle such issues in the management plan for better results Keywords: psoriasis, pathogenesis of psoriasis, management of psoriasis, impact on quality of life in psoriatic patients.