Pathogenesis of the downer cow syndrome

Cox, Victor S

doi:10.1136/vr.111.4.76

Cited by 51 publications

(79 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A relapse after an initial response to treatment is considerably less detrimental than a total lack of response. Experimentally-induced downer cow syndrome (healthy anaesthetised cows maintained in sternal recumbency) resulted in ischaemic muscle necrosis of the pelvic limb that was positioned under the body after 6 to 12 hours of recumbency (Cox et al, 1982). In the current study, 2 cows of group A but none of group B had to be euthanized because of downer cow syndrome; in the study by Dumelin (2005), 2 cows of the control group and one cow that received oral phosphorus had downer cow syndrome.…”

Section: Discussionmentioning

confidence: 99%

Treatment of cows with parturient paresis using intravenous calcium and oral sodium phosphate

Braun

Grob

Hässig

2016

SAT

View full text Add to dashboard Cite

The goal of this study was to investigate whether intravenous infusion of 1000 ml 40% calcium borogluconate combined with the oral adminstration of 500 g sodium phosphate leads to a better cure rate and longer-lasting normocalcaemia and normophosphataemia than standard intravenous treatment with 500 ml calcium borogluconate in cows with parturient paresis. Forty recumbent cows with hypocalcaemia and hypophosphataemia were alternately allocated to group A or B. Cows of both groups were treated intravenously with 500 ml 40% calcium borogluconate, and cows of group B additionally received another 500 ml calcium borogluconate via slow intravenous infusion and 500 g sodium phosphate administered via an orogastric tube. Thirty-two cows stood within 8 hours after the start of treatment and 8 did not; of the 32 cows that stood, 18 belonged to group A and 14 to group B (90% of group A vs. 70% of group B; P = 0.23). Seven cows relapsed; of these and the 8 that did not respond to initial treatment, 10 stood after two standard intravenous treatments. Downer cow syndrome occurred in 5 cows, 3 of which recovered after aggressive therapy. The overall cure rate did not differ significantly between groups A and B. Twelve (60%) cows of group A and 14 (70%) cows of group B were cured after a single treatment and of the remaining 14, 11 were cured after two or more treatments. Two downer cows were euthanized and one other died of heart failure during treatment. Serum calcium concentrations during the first eight hours after the start of treatment were significantly higher in group B than in group A, and oral sodium phosphate caused a significant and lasting increase in inorganic phosphate. More cows of group B than group A were cured after a single treatment (P > 0.05). These findings, although not statistically significant, are promising and should be verified using a larger number of cows. DOI: https://doi.org/10.17236/sat00081Other titles: Behandlung der Gebärparese von Kühen mit Kalzium intravenös und Natriumphosphat per os Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-130508 Veröffentlichte Version Originally published at: Braun, Ueli; Grob, Daniela; Hässig, Michael (2016). Treatment of cows with parturient paresis using intravenous calcium and oral sodium phosphate. Schweizer Archiv für Tierheilkunde, 158(9):615-622.

show abstract

Section: Discussionmentioning

confidence: 99%

Treatment of cows with parturient paresis using intravenous calcium and oral sodium phosphate

Braun

Grob

Hässig

2016

SAT

View full text Add to dashboard Cite

show abstract

“…If treatment is delayed or if the cow fails to respond, the prospects for successful treatment become remote (Cox 1982). Furthermore, there is some evidence that milk fever causes a reduction in the productive life of the cow (Leech et al 1964).…”

Section: Introductionmentioning

confidence: 99%

Failure of 25-hydroxycholecalciferol to prevent milk fever in dairy cows

Allsop¹,

Pauli

1985

New Zealand Journal of Experimental Agriculture

View full text Add to dashboard Cite

An intramuscular injection of 4 mg of 25-hydroxycholecalciferol [25(OH)D)l in com oil was administered 3-10 days before calving to 123 cows of third or subsequent lactation on 6 dairy farms. There were no significant differences in the prevalence and severity of milk fever or in the level of plasma calcium within 24 h of calving between the injected cows and paired control animals. Cows with milk fever were significantly older than those without, but were no different in circulating 25(OH)D) levels or in condition score. The prevalence of milk fever in the selected cows in each herd ranged from 0 to 26% and was correlated with the calcium content of the hay supplement fed prior to parturition.

show abstract

“…Analgesics are useful in maintaining the comfort and appetite of the recumbent animal (Rebhun, 1995c;Ciszewski and Ames, 1987;Cox, 1981).…”

Section: Outcomementioning

confidence: 99%

Scientific report on the effects of farming systems on dairy cow welfare and disease

2009

EFSA Journal

View full text Add to dashboard Cite

Pathogenesis of the downer cow syndrome

Cited by 51 publications

References 0 publications

Treatment of cows with parturient paresis using intravenous calcium and oral sodium phosphate

Treatment of cows with parturient paresis using intravenous calcium and oral sodium phosphate

Failure of 25-hydroxycholecalciferol to prevent milk fever in dairy cows

Scientific report on the effects of farming systems on dairy cow welfare and disease

Contact Info

Product

Resources

About