Pathogenesis of Post-Traumatic Stress Disorder, Therapeutic Targets
M. S. Lapshin,
M. V. Kondashevskaya,
V. V. Epishev
et al.
Abstract:Abstract—The review summarizes current literature information on the mechanisms of pathogenesis of severe stress-induced disease – post-traumatic stress disorder (PTSD). Hormonal, biochemical, genetic and morphofunctional changes in peripheral organs and in the central nervous system occurring in PTSD are characterized. It turned out that most researchers have formed an opinion about the leading role of chronic inflammation in PTSD. The data on the study of the action of anti-inflammatory drugs with a narrow b… Show more
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