Pathogenesis of Angina Pectoris

Fuchs, Richard M.; Becker, Lewis C.

doi:10.1001/archinte.1982.00340220105018

Cited by 14 publications

(1 citation statement)

References 122 publications

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“…However, it is short-lasting and undergoes the first-pass metabolism. Hence, longer-acting nitrates such as isosorbide dinitrate have been used in treatment [73]. It was found that drugs such as ivabradine in tablet form lowered the heart rate, but their pharmacokinetic property were poor.…”

Section: Therapeutic and Theranostic Applications Of Targeted Nanomed...mentioning

confidence: 99%

Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives

et al. 2022

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Cardiovascular and related diseases (CVRDs) are among the most prevalent chronic diseases in the 21st century, with a high mortality rate. This review summarizes the various nanomedicines for diagnostic and therapeutic applications in CVRDs, including nanomedicine for angina pectoris, myocarditis, myocardial infarction, pericardial disorder, thrombosis, atherosclerosis, hyperlipidemia, hypertension, pulmonary arterial hypertension and stroke. Theranostic nanomedicines can prolong systemic circulation, escape from the host defense system, and deliver theranostic agents to the targeted site for imaging and therapy at a cellular and molecular level. Presently, discrete non-invasive and non-surgical theranostic methodologies are such an advancement modality capable of targeted diagnosis and therapy and have better efficacy with fewer side effects than conventional medicine. Additionally, we have presented the recent updates on nanomedicine in clinical trials, targeted nanomedicine and its translational challenges for CVRDs. Theranostic nanomedicine acts as a bridge towards CVRDs amelioration and its management.

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Section: Therapeutic and Theranostic Applications Of Targeted Nanomed...mentioning

confidence: 99%