“…We chose this approach to avoid stress associated with forced exercise protocols in the dams. Recent studies have reported that paternal exercise (>3 weeks) can mitigate the detrimental effects of paternal obesity on offspring glucose tolerance, adiposity, and pancreatic β-cell mass; vascular function was not assessed (McPherson, Lane, Sandeman, Owens, & Fullston, 2017;McPherson, Owens, Fullston, & Lane, 2015;Stanford et al, 2018). In our study, the mating pairs were set up nightly and males were removed immediately after breeding was confirmed (visible by a vaginal plug).…”