Paternal Death, Parental Divorce, and Timing of First Substance Use in an Ethnically Diverse Sample

Doran, Kelly; Watkins, Nicole K.; Duckworth, Jennifer C.; Waldron, Mary

doi:10.1080/1067828x.2019.1580234

Cited by 7 publications

(2 citation statements)

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“…In an extensive narrative review of the literature, Lytje and Dyregrov 8 reported that the consequences of parental death relate to psychological, physical and social domains. With regard to health, the death of a parent in childhood or adolescence has been shown to be significantly associated with deleterious outcomes across a range of areas including mental health, 7,9 physical health 10 and substance use 11 . In a recent meta‐analysis of case‐control studies, Simbi et al 12 reported that those experiencing parental death in childhood or adolescence were 1.76 times more likely to suffer from depression in later adult life, than controls.…”

Section: Introductionmentioning

confidence: 99%

“…With regard to health, the death of a parent in childhood or adolescence has been shown to be significantly associated with deleterious outcomes across a range of areas including mental health, 7,9 physical health 10 and substance use. 11 In a recent meta-analysis of case-control studies, Simbi et al 12 reported that those experiencing parental death in childhood or adolescence were 1.76 times more likely to suffer from depression in later adult life, than controls. Beyond health, the impact of the death of a parent can result in lower self-esteem, poorer educational outcomes and an increased likelihood to become involved in violent criminal behaviour.…”

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confidence: 99%

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A meta‐analysis of the relationship between parental death in childhood and subsequent psychiatric disorder

McKay

Cannon

Healy

et al. 2021

Acta Psychiatr Scand

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Objective To systematically review evidence for an association between parental death in childhood, and the subsequent development of an anxiety, affective or psychotic disorder. Methods Electronic databases (Scopus, Medline (for Ovid), EMBASE and PsychINFO) were searched for peer‐reviewed, cohort studies in the English language. Meta‐analyses were performed for studies reporting hazard ratios, incidence rate ratios and odds ratios. Two studies reported risk ratios, and these were included in an overall pool of odds, risk and incidence rate ratios. Sensitivity analyses were performed (removal of one study at a time) for all meta‐analyses, and study quality assessed using the Newcastle‐Ottawa Scale. Results Fifteen studies were retained, and where required, data were averaged in advance of pooling. Significant results were observed in studies reporting hazard ratios (k = 4, 1.48 [95% CI = 1.32–1.66]), incidence rate ratios (k = 3, 1.37 [95% CI = 1.01–1.85]), but not odds ratios (k = 4, 0.87 [95% CI = 0.72, 1.05]). However, the overall pooled effect (using odds, incidence rate and risk ratios) was statistically significant (k = 9, 1.22 [95% CI = 1.03–1.44]). Conclusion Overall, the evidence suggests that there is a positive association between the death of a parent before age 18, and the subsequent development of an anxiety, affective or psychotic disorder. The lack of a significant pooled effect in studies reporting results as odds ratios is likely an artefact of study design. Limitations Data were clustered in four countries making generalizability uncertain. Studies adjusted for a variety of possible confounders, and follow‐up after death varied considerably.

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