The rapid increase in the number of university-enterprise patent cooperation shows that the university-enterprise cooperation innovation has achieved certain results. However, the quality of school enterprise cooperation is still worrying. Therefore, based on the total patent data of China's university-enterprise cooperation from 1985 to 2020, this passage analyzes the innovation performance of China's university enterprise cooperation from the perspective of patent quality from three aspects of technology, economy and law. Based on the analysis of the data, it is found that the quality of university-enterprise cooperation patents has improved, the market layout is relatively perfect, and the legal status of patents is generally good. But there are also some problems, such as low level of patent technology, scattered R & D team, low efficiency of patent operation, poor market competitiveness, poor patent stability, and poor awareness of patent protection. Finally, the corresponding countermeasures and suggestions are put forward.