Patagonian berries as native food and medicine

Schmeda‐Hirschmann, Guillermo; Jiménez‐Aspee, Felipe; Theoduloz, Cristina; Ladio, Ana Haydeé

doi:10.1016/j.jep.2019.111979

Cited by 42 publications

(50 citation statements)

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regarding the polyphenol composition of the Patagonian berries, Maqui and Calafate have anthocyanins as the main molecule (Brito et al 2014;Fuentes et al 2016;Ruiz et al 2010Ruiz et al , 2013aSchmeda-Hirschmann et al 2019;Simirgiotis et al 2013;Ulloa-Inostroza et al 2017). As expected, our results showed that anthocyanin-rich extracts of Calafate fruits presented higher total anthocyanin concentration (32 mg cyanidin 3-O-glucoside g −1 DW) compared to crude extracts (25 mg cyanidin 3-O-glucoside g −1 DW), which were increased concomitant at increasing extract concentration.…”

Section: Discussionsupporting

confidence: 79%

“…Plant phenolics have radical scavenging and metal chelating potential, being useful to the treatment of worldwide diseases like cardiovascular disorders and cancer (Mocan et al 2016). In Chilean Patagonia, edible fruits of the woody or shrub forest species belonging to the Berberidaceae family, such as Calafate, are rich in antioxidant compounds (Brito et al 2014;Fuentes et al 2016;Ruiz et al 2010;Schmeda-Hirschmann et al 2019;Simirgiotis et al 2013;Ulloa-Inostroza et al 2017). Our results showed that the antioxidant activity, as well as total phenols and total anthocyanin content of Calafate extracts, increased concomitant with the increase of extract concentrations.…”

Section: Discussionmentioning

confidence: 60%

See 1 more Smart Citation

Anthocyanin-Rich Extracts of Calafate (Berberis microphylla G. Forst.) Fruits Decrease In Vitro Viability and Migration of Human Gastric and Gallbladder Cancer Cell Lines

Calderón-Reyes

Pezoa

Leal

et al. 2020

J Soil Sci Plant Nutr

View full text Add to dashboard Cite

Currently, gastric cancer (GC) and gallbladder cancer (GBC) constitute important causes of human deaths related to cancer worldwide. In the last years, several researches are focused on the role of dietary compounds in preventing cancers. The consumption of fruits with high antioxidants, mainly anthocyanins, represents a good option to reduce the risk of chronic human diseases. Calafate (Berberis microphylla G. Forst.) berries, recognized by their remarkable antioxidant properties and high content of anthocyanins, appear as a new alternative to treat degenerative diseases of public interest. The present work was aimed to evaluate the impact of crude and anthocyanin-rich extracts from Calafate fruits on in vitro cell viability and migration capacity of gastric (AGC) and gallbladder (G415) human cancer cell lines, as related with their antioxidant properties. Crude and anthocyanin-rich extracts were obtained from fruits of Calafate grown under field conditions in the south of Chile. Antioxidants, phenols, anthocyanins, and anthocyanidins were determined. In vitro cell viability and migration of AGS and G415 human cancer cell lines at different concentrations of extracts (25-800 μg mL −1) were determined. Anthocyanin-rich extracts of Calafate berries showed comparable antioxidant activity (up to 1200 μg Trolox eq. g −1 DW), slightly lower total phenolic content (12%), but higher total anthocyanin content (25%) compared to the crude extract. The major anthocyanidin molecule detected in both extracts was delphinidin, followed by malvidin, and low concentrations of petunidin, cyanidin, and peonidin. As expected, all of these compounds were detected in higher levels in anthocyanin-rich extracts (up to 2-fold). Noteworthy, our study revealed that Calafate fruit extracts strongly decrease in vitro viability and migration capacity of gastric carcinoma (AGC model) and gallbladder carcinoma (G415 model) human cell lines; however, the anthocyanin-rich extract displayed higher inhibitory effects (up to 70%) compared to crude extracts. These findings allow suggesting that the in vitro antiproliferative potential of Calafate fruit extract is strongly related to the anthocyanin concentration, especially delphinidin.

show abstract

Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 60%

Anthocyanin-Rich Extracts of Calafate (Berberis microphylla G. Forst.) Fruits Decrease In Vitro Viability and Migration of Human Gastric and Gallbladder Cancer Cell Lines

Calderón-Reyes

Pezoa

Leal

et al. 2020

J Soil Sci Plant Nutr

View full text Add to dashboard Cite

show abstract

“…Calafate ( Berberis microphylla ) has presented unique properties due to the high variety of health associated compounds, such as phenols, vitamins, minerals and amino acids [ 1 ]. Calafate belongs to the family Berberidaceae, and the fruits are harvested in numerous Chilean and Argentinian Patagonian sectors [ 2 ]. However, calafate production is still low compared to other berries (2019: 0.2 hectares calafate versus 970.6, 9.0 and 2.9 hectares of blueberries ( Vaccinium corymbosum ), maqui ( Aristotelia chilensis ) and michay ( Berberis darwinii ), respectively).…”

Section: Introductionmentioning

confidence: 99%

Quality Attributes of Cryoconcentrated Calafate (Berberis microphylla) Juice during Refrigerated Storage

Orellana‐Palma

Tobar-Bolaños

Casas-Forero

et al. 2020

Foods

View full text Add to dashboard Cite

This study aimed to evaluate the potential of centrifugal block cryoconcentration (CBCC) at three cycles applied to fresh calafate juice. The fresh juice and cryoconcentrate at each cycle were stored for five weeks at 4 °C and quality attributes were analyzed every 7 days. CBCC had significant effects in the calafate juice, since in the last cycle, the cryoconcentrate reached a high value of total soluble solids (TSS, ≈42 °Brix), with final attractive color, and an increase of approximately 2.5, 5.2, 5.1, 4.0 and 5.3 times in relation to the fresh juice values, for total bioactive compounds (TBC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), ferric reducing antioxidant power (FRAP) and oxygen radical absorbance capacity (ORAC), respectively. However, at 35 days under storage, these values decreased by 5%, 13%, 15%, 19%, 24% and 27%, for TSS, TBC, DPPH, ABTS, FRAP and ORAC, respectively. Additionally, until the day 14, the panelists indicated a good acceptability of the reconstituted cryoconcentrate. Therefore, CBCC can be considered a novel and viable technology for the preservation of quality attributes from fresh calafate juice with interesting food applications of the cryoconcentrates due to their high stability during storage time in comparison to the fresh juice.

show abstract

“…In the last few decades, the interest in wild edible herbs has increased thanks to their already known medicinal properties [ 1 , 2 , 3 , 4 ], as well as their use in dietary supplements as a source of nutraceutical properties and bioactive compounds [ 5 , 6 , 7 , 8 ]. This is due to the high content of phytochemicals found in many wild edible species, which makes them useful as a “new” functional food.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Three Domestications and Wild-Harvested Plants for Nutraceutical Properties and Sensory Profiles in Five Wild Edible Herbs: Is Domestication Possible?

Ceccanti

Landi

Incrocci

et al. 2020

Foods

View full text Add to dashboard Cite

In this study, five wild edible herbs traditionally consumed in the Tuscany region (Italy) were evaluated for their potential in human nutrition. The nutraceutical characterization of Rumex acetosa, Cichorium intybus, Picris hieracioides, Sanguisorba minor, and Plantago coronopus, as well as their sensory profile were reported. Additionally, a preliminary assessment of completely different domestication of the wild species (named “soilless”, pot, and open field) was conducted to verify the possibility of their marketability, which is impossible if the plants are only gathered as wild. The open field domestication allowed to obtain plants with nutraceutical and sensory profiles similar to those of the wild species, especially in C. intybus, P. hieracioides, and S. minor. The pot domestication allow to obtain plants with chlorophyll and carotenoid contents close to those of the wild species, as well as a lower total phenolic and flavonoid content and ascorbic acid content than wild species. In the “soilless” method, R. acetosa and P. coronopus exhibited a high quality in terms of phytochemicals and antioxidant activity. Afterward, the sensory profile was strongly affected by the domestication in terms of the palatability, except for R. acetosa and P. coronopus, which displayed Hedonic Index (HI) values close to the consumer acceptability limit (HI = 6). A sensory profile similar to that of wild species was reported in open field domestication, whereas a worse sensory profile was reported in P. hieracioides and C. intybus domesticated using the soilless method. Finally, according to the preliminary assessment carried out in this study through an analysis of the general nutraceutical properties, S. minor was shown to be the most promising species thanks to its intrinsically highest nutraceutical properties considering the marketability of wild edible herbs as “new” functional food. However, further research on the bioavailability and bioactivity tests of nutraceutical compounds present in this species are required to confirm the findings of this study.

show abstract

Patagonian berries as native food and medicine

Cited by 42 publications

References 82 publications

Anthocyanin-Rich Extracts of Calafate (Berberis microphylla G. Forst.) Fruits Decrease In Vitro Viability and Migration of Human Gastric and Gallbladder Cancer Cell Lines

Anthocyanin-Rich Extracts of Calafate (Berberis microphylla G. Forst.) Fruits Decrease In Vitro Viability and Migration of Human Gastric and Gallbladder Cancer Cell Lines

Quality Attributes of Cryoconcentrated Calafate (Berberis microphylla) Juice during Refrigerated Storage

Comparison of Three Domestications and Wild-Harvested Plants for Nutraceutical Properties and Sensory Profiles in Five Wild Edible Herbs: Is Domestication Possible?

Contact Info

Product

Resources

About