2021
DOI: 10.1016/j.scitotenv.2021.145585
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Past, present, and future perspectives on the assessment of bioavailability/bioaccessibility of polycyclic aromatic hydrocarbons: A 20-year systemic review based on scientific econometrics

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Cited by 30 publications
(5 citation statements)
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“…The detection of PAHs in environmental concentrations as well as the understanding of their biological effects and health risks are areas of research that are currently hotspots. Future research should be devoted to (i) establishing precise and high-efficiency analytical methods for PAH detection in environmental concentrations; (ii) the development of unambiguous animal model studies to understand biological effects in vivo; (iii) the development of unambiguous in vitro models; and (iv) introducing omics methodologies in risk assessment, which can be used to identify environmental exposures related to health and disease as well as epidemiological investigations and biomarker detection [ 161 ]. Current research is underway to improve the LODs for field application, as well as to improve current analytical methods.…”
Section: Polycyclic Aromatic Hydrocarbons (Pahs)mentioning
confidence: 99%
“…The detection of PAHs in environmental concentrations as well as the understanding of their biological effects and health risks are areas of research that are currently hotspots. Future research should be devoted to (i) establishing precise and high-efficiency analytical methods for PAH detection in environmental concentrations; (ii) the development of unambiguous animal model studies to understand biological effects in vivo; (iii) the development of unambiguous in vitro models; and (iv) introducing omics methodologies in risk assessment, which can be used to identify environmental exposures related to health and disease as well as epidemiological investigations and biomarker detection [ 161 ]. Current research is underway to improve the LODs for field application, as well as to improve current analytical methods.…”
Section: Polycyclic Aromatic Hydrocarbons (Pahs)mentioning
confidence: 99%
“…For example, visual analysis has been conducted on the field of psycho-cardiology over the past 20 years [12], and CiteSpace and VOSViewer have been employed to analyze literature related to crowd evacuation [13]. Additionally, a quantitative analysis and systematic review of published articles in the field of electrochemiluminescence from 2000 to 2021 has been conducted [14], along with a discussion on research advances in the bioavailability assessment of polycyclic aromatic hydrocarbons (PAHs) and recent research priorities [15]. Bibliometrics enable a systematic analysis of the research landscape and the organization of existing theoretical frameworks, as well as providing strong support for constructing the knowledge foundations, exploring frontiers, and identifying development trends in a particular field.…”
Section: Introductionmentioning
confidence: 99%
“…Bioaccessibility of food contaminants can be assessed using an in vitro digestion model that mimics the physiological/biochemical conditions in the human GIT [ 10 ]. Regarding the bioaccessibility of PAHs, most of the studies focus on soil as the matrix, assessing human uptake of PAHs in soil [ 11 , 12 , 13 , 14 ], while limited study has been performed for the bioaccessibility of PAHs contained in food. Few studies have reported on the bioaccessibility of PAHs in seafood, uncooked animal-based foods and cereal after an in vitro human digestion [ 15 , 16 , 17 , 18 ]; however, little is known about the bioaccessibility of PAHs contained in charcoal-grilled meat in the human GIT.…”
Section: Introductionmentioning
confidence: 99%