Passive smoking and mortality from aortic dissection or aneurysm

Kihara, Takanori; Yamagishi, Kazumasa; Iso, Hiroyasu; Tamakoshi, Akiko

doi:10.1016/j.atherosclerosis.2017.06.022

Cited by 28 publications

(21 citation statements)

References 21 publications

(27 reference statements)

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“…Twenty three prospective studies (22 publications) 7 , 16 – 36 were included in the meta-analysis of smoking and risk of abdominal aortic aneurysms (Fig. 1 , Supplementary Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…Twenty studies (18 publications) 7 , 16 , 18 , 19 , 22 , 23 , 25 – 36 of current smokers (8901 cases, 4716185 participants), fifteen studies (thirteen publications) 7 , 19 , 22 , 23 , 25 – 27 , 29 – 31 , 33 , 35 , 36 of former smokers (7824 cases, 3060503 participants), and eighteen studies (16 publications) 7 , 16 , 17 , 19 , 22 , 23 , 25 – 27 , 29 , 30 , 32 – 36 of ever smokers (8448 cases, 3934635 participants) and abdominal aortic aneurysms were included in the analyses. The summary RR for current smokers vs. never smokers was 4.87 (95% CIs: 3.93–6.02, I 2 = 91.5%, p heterogeneity < 0.0001) (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Although a large number of studies have found a positive association between smoking and risk of abdominal aortic aneurysm 7 , 16 – 36 , there has been variation observed with regard to the strength of the association between studies and by sex, with stronger associations observed in women than in men in some 30 , 33 , although not all studies 22 , 32 , 34 . Several studies found a dose-response relationship between the intensity of smoking and risk of abdominal aortic aneurysms 7 , 18 , 28 , 29 , however, in a few studies there was a flattening of the curve with a larger number of cigarettes smoked per day 20 , 22 , 25 , 27 .…”

Section: Introductionmentioning

confidence: 99%

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Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Aune

Schlesinger

Norat

et al. 2018

Sci Rep

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Several studies have found that smoking increases the risk of abdominal aortic aneurysm, however, the strength of the association has differed between studies and data from cohort studies have not yet been summarized. A systematic review and meta-analysis was therefore conducted to clarify this association. We searched PubMed and Embase databases up to May 2nd 2018. A random effects model was used to estimate summary relative risks (RRs) and 95% confidence intervals (CIs). Twenty three prospective studies were included. Comparing current, former and ever smokers with never smokers the summary RRs were 4.87 (95% CI: 3.93–6.02, I2 = 92%, n = 20), 2.10 (95% CI: 1.76–2.50, I2 = 71%, n = 15) and 3.28 (95% CI: 2.60–4.15, I2 = 96%, n = 18), respectively. The summary RR was 1.87 (95% CI: 1.45–2.40, I2 = 97%) per 10 cigarettes per day, 1.78 (95% CI: 1.54–2.06, I2 = 83%) per 10 pack-years was and 0.45 (95% CI: 0.32–0.63, I2 = 92.3%) per 10 years of smoking cessation. There was evidence of nonlinearity for cigarettes per day and pack-years (pnonlinearity < 0.0001 and pnonlinearity = 0.02, respectively), but not for smoking cessation, pnonlinearity = 0.85. Among smokers who quit, the RR was similar to that of never smokers by 25 years of smoking cessation. These findings confirm a strong association between smoking and the risk of developing abdominal aortic aneurysms.

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“…Twenty three prospective studies (22 publications) 7 , 16 – 36 were included in the meta-analysis of smoking and risk of abdominal aortic aneurysms (Fig. 1 , Supplementary Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Aune

Schlesinger

Norat

et al. 2018

Sci Rep

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“…HF was found to be a risk factor for 30-day readmission after infrarenal AA repair [12]. Smoking is associated with increased mortality from AAs [13]. Compared with women, male smokers are more likely to develop AF [14].…”

Section: Discussionmentioning

confidence: 99%

Association between Atrial Fibrillation and Aortic Aneurysms: A Population-Based Cohort Study

et al. 2018

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Objective: Atrial fibrillation (AF) is the most common form of sustained arrhythmia. Several molecular pathways associated with the pathogenesis of AF also participate in the initiation and progression of aortic aneurysm (AA). In this study, we aimed to evaluate potential associations between AA and AF. Patients and Methods: The data for this nationwide population-based retrospective cohort study were obtained from Taiwan’s National Health Insurance Research Database (NHIRD). All medical conditions for each case and the controls were categorized using the 9th revision of the International Classification of Diseases (ICD-9). Odds ratios and 95% confidence intervals for associations between AF and AA were estimated using Cox regression and adjusted for comorbidities. Results: Our analyses included 116,225 AF cases and 116,225 propensity score-matched controls. Compared with the controls, the patients with AF exhibited a significantly increased risk of developing an AA (adjusted hazard ratio, HR 1.243, p < 0.001). Another cohort of 19,776 patients diagnosed with AA were identified, and 19,776 propensity score-matched patients were included as controls. Patients who had AA were also at an increased risk of developing AF (adjusted HR 1.187, p < 0.001). Heart failure (HF) was a common risk factor for both AA and AF. Conclusion: There are associations between AF and AA. HF is a mutual risk factor for the development of AF and AA.

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“…Fifth, we had no data on passive smoking, which is also associated with aortic disease mortality. 28 Finally, we had no information on the medication used by this population.…”

Section: Study Limitationsmentioning

confidence: 99%

Effect of Hypertension on Aortic Artery Disease-Related Mortality　― 3.8-Year Nationwide Community-Based Prospective Cohort Study ―

Otaki

Watanabe

Konta

et al. 2018

Circ J

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The prevalence of hypertension (HT) is still increasing and is a well-known risk for cardiovascular disease and mortality. The mechanisms by which HT is involved in the development of cardiovascular disease includes several complex processes such as the sympathetic nervous system, renin-angiotensin-aldosterone system (RAAS), and oxidative stress. 5 Several guidelines, such as the Japanese Society of Hypertension (JSH) 2014, recommend lowering blood pressure (BP) to <140 and <90 mmHg for the primary A ortic artery disease (AAD), namely aortic artery dissection or aortic aneurysm rupture, is a major cause of sudden death. 1,2 In almost all cases of aortic aneurysm rupture, the patient dies before arriving at hospital; furthermore, the mortality rate ≤24 h after symptom onset reaches approximately 50-70% despite surgical treatment. 3 Similarly, the mortality rates in those with ascending aortic dissection between 24 h and 1 month after onset are 20% and 50%, respectively. 4 Therefore, it is critical to identify high-risk subjects and prevent the development of AAD in apparently healthy subjects using health checkups .

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Passive smoking and mortality from aortic dissection or aneurysm

Abstract: Background and aims: Evidence on the association between passive smoking and risk

Cited by 28 publications

References 21 publications

Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Association between Atrial Fibrillation and Aortic Aneurysms: A Population-Based Cohort Study

Effect of Hypertension on Aortic Artery Disease-Related Mortality　― 3.8-Year Nationwide Community-Based Prospective Cohort Study ―

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Passive smoking and mortality from aortic dissection or aneurysm

Abstract: Background and aims: Evidence on the association between passive smoking and risk

Cited by 28 publications

References 21 publications

Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Tobacco smoking and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

Association between Atrial Fibrillation and Aortic Aneurysms: A Population-Based Cohort Study

Effect of Hypertension on Aortic Artery Disease-Related Mortality ― 3.8-Year Nationwide Community-Based Prospective Cohort Study ―

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Product

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About

Effect of Hypertension on Aortic Artery Disease-Related Mortality　― 3.8-Year Nationwide Community-Based Prospective Cohort Study ―