Passive shimming of the fringe field of a superconducting magnet for ultra-low field hyperpolarized noble gas MRI

Parra‐Robles, Juan; Cross, Albert R.; Santyr, Giles

doi:10.1016/j.jmr.2005.01.016

Cited by 3 publications

(2 citation statements)

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“…Moreover, Xe-129 has advantages for measuring both chemical and physical diffusion using MRI, as well as for T2-weighted acquisitions at lower field strengths. Several research sites are developing low field scanners dedicated to lung imaging (56,117). Low-field systems (Fig.…”

Section: Discussionmentioning

confidence: 99%

Functional lung imaging using hyperpolarized gas MRI

Fain

Korosec

Holmes

et al. 2007

Magnetic Resonance Imaging

178

158

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The noninvasive assessment of lung function using imaging is increasingly of interest for the study of lung diseases, including chronic obstructive pulmonary disease (COPD) and asthma. Hyperpolarized gas MRI (HP MRI) has demonstrated the ability to detect changes in ventilation, perfusion, and lung microstructure that appear to be associated with both normal lung development and disease progression. The physical characteristics of HP gases and their application to MRI are presented with an emphasis on current applications. Clinical investigations using HP MRI to study asthma, COPD, cystic fibrosis, pediatric chronic lung disease, and lung transplant are reviewed. Recent advances in polarization, pulse sequence development for imaging with Xe-129, and prototype low magnetic field systems dedicated to lung imaging are highlighted as areas of future development for this rapidly evolving technology.

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Section: Discussionmentioning

confidence: 99%

Functional lung imaging using hyperpolarized gas MRI

Fain

Korosec

Holmes

et al. 2007

Magnetic Resonance Imaging

178

158

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show abstract

“…Hyperpolarized natural abundance xenon gas (26.4% 129 Xe) was produced using a continuous-flow polarization system that used a 60 W diode array laser (k = 794.8 nm, Coherent, Santa Clara, USA) and a gas mixture of 1% xenon, 10% nitrogen and 89% helium and produced 129 Xe polarizations of up to 22% [16,17]. In order to minimize depolarization of the hyperpolarized 129 Xe by paramagnetic molecular oxygen, the air inside the phantom was initially flushed out by flowing the gas mixture through the phantom for about 30 s. The phantom was then evacuated using a syringe and a three-way valve, before delivering pure hyperpolarized xenon (cryo-trapped using liquid Fig.…”

Section: Hng Production and Delivery To Phantomsmentioning

confidence: 99%

Theoretical prediction and experimental measurement of the field dependence of the apparent transverse relaxation of hyperpolarized noble gases in lungs

Parra‐Robles

Viqueira

et al. 2008

Journal of Magnetic Resonance

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Magnetic Resonance Imaging

Block¹,

Alexander²,

Fain³

et al. 2006

Encyclopedia of Medical Devices and Instrumentation

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Magnetic resonance imaging (MRI) moved out of the exclusive realm of academia and into widespread clinical practice in the 1980s. Relatively quickly, MRI became the modality of choice for several head, spine, and musculoskeletal imaging exams due to tis excellent soft tissue contrast. Although the plateau of MRI’s development and utilization has often been predicted, it continues to grow through being an amazingly adaptive technology. New mechanisms of generating image contrast have allowed the modality to go beyond the study of anatomical structure and deliver functional physiological informaion. A description of the nuclear magnetic resonance (NMR) phenomena, methods to spatially encode the NMR signal, image contrast mechanisms, and emerging appliactions are provided.

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Passive shimming of the fringe field of a superconducting magnet for ultra-low field hyperpolarized noble gas MRI

Cited by 3 publications

References 20 publications

Functional lung imaging using hyperpolarized gas MRI

Functional lung imaging using hyperpolarized gas MRI

Theoretical prediction and experimental measurement of the field dependence of the apparent transverse relaxation of hyperpolarized noble gases in lungs

Magnetic Resonance Imaging

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