Passive Heating As An Option For Improving Glucose Control

Abstract

Obesity and type 2 diabetes are increasing in prevalence and can be treated by lifestyle interventions such as diet and exercise. Acute exercise has an insulin sensitising effect, leading to improved glucose control. This may in part be due to the attenuated synthesis of heat shock protein 70 (HSP70) in obesity and diabetes. HSP70 may be elevated by exercise and passive heating (PH). Furthermore, animal studies suggest PH may be beneficial to glucose control. PURPOSE: To determine the effect of PH versus exercise on the HSP70 response and glucose control in overweight and lean humans.