Parylene C as an Insulating Polymer for Implantable Neural Interfaces: Acute Electrochemical Impedance Behaviors in Saline and Pig Brain In Vitro

Zhang, Yuan; Zhang, Jing; Song, Liang‐Nian; Niu, Lan; Jin, Tao; Liang, Jinsong; Zhang, Lihua; Kang, Xiaoyang

doi:10.3390/polym14153033

Cited by 2 publications

(2 citation statements)

References 55 publications

(73 reference statements)

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“…For additional safety concerns, a thin protective coating with good biocompatibility, such as parylene, can be applied to the surface of the iWood device. [ 25 ]…”

Section: Resultsmentioning

confidence: 99%

iWood: An Intelligent Iontronic Device for Human‐Wood Interactions

Li,

Ge,

et al. 2024

Adv Funct Materials

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Woodwork is involved in a variety of interactions with humans through physical contact, which may reveal valuable information if the tactile data can be unnoticeably extracted. In this work, an intelligent iontronic wood (iWood) device, along with its seamlessly integrated architecture into the woodwork, enabled by the iontronic sensing principle, is implemented. Notably, the tactile sensing structure is generated at the iontronic interface between ionic and conductive woods. In particular, the ionic wood is established by infusing an ionic liquid into the wood, followed by immobilizing it via chemical bonding, presenting both prominent ionic conductivity and excellent stability under pressure. By formatting the woods into identical strips, the high‐density tactile sensing array can be simply formed by a braiding process for a scalable interwoven structure. As a result, the iWood device has offered a high sensitivity over a broad detection of 0.5 MPa and an array of 40 × 90 units covering an area up to 3600 cm2. The iWood device is showcased as an interactive human interface, demonstrating its potential as a smart desktop capable of gesture and object recognition, a health‐tracking chair for real‐time ballistocardiograph monitoring, and an embedded intelligent floor for weight management and gait analysis.

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“…For additional safety concerns, a thin protective coating with good biocompatibility, such as parylene, can be applied to the surface of the iWood device. [ 25 ]…”

Section: Resultsmentioning

confidence: 99%

iWood: An Intelligent Iontronic Device for Human‐Wood Interactions

Li,

Ge,

et al. 2024

Adv Funct Materials

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“…However, their irregular and repetitive movement hinders the uniform operation of such devices for long-term use. Encapsulation layers made of conventional encapsulation materials are breakable, resulting in a loss of function when external-damage-induced breaks are applied [ 39 , 40 , 41 , 42 , 43 ]. The devices may be damaged owing to the penetration of bodily fluid.…”

Section: Introductionmentioning

confidence: 99%

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

Lyu

Seong

et al. 2023

Polymers

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Polymers for implantable devices are desirable for biomedical engineering applications. This study introduces a water-resistant, self-healing fluoroelastomer (SHFE) as an encapsulation material for antennas. The SHFE exhibits a tissue-like modulus (approximately 0.4 MPa), stretchability (at least 450%, even after self-healing in an underwater environment), self-healability, and water resistance (WVTR result: 17.8610 g m−2 day−1). Further, the SHFE is self-healing in underwater environments via dipole–dipole interactions, such that devices can be protected from the penetration of biofluids and withstand external damage. With the combination of the SHFE and antennas designed to operate inside the body, we fabricated implantable, wireless antennas that can transmit information from inside the body to a reader coil that is outside. For antennas designed considering the dielectric constant, the uniformity of the encapsulation layer is crucial. A uniform and homogeneous interface is formed by simply overlapping two films. This study demonstrated the possibility of wireless communication in vivo through experiments on rodents for 4 weeks, maintaining the maximum communication distance (15 mm) without chemical or physical deformation in the SHFE layer. This study illustrates the applicability of fluoroelastomers in vivo and is expected to contribute to realizing the stable operation of high-performance implantable devices.

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Parylene C as an Insulating Polymer for Implantable Neural Interfaces: Acute Electrochemical Impedance Behaviors in Saline and Pig Brain In Vitro

Cited by 2 publications

References 55 publications

iWood: An Intelligent Iontronic Device for Human‐Wood Interactions

iWood: An Intelligent Iontronic Device for Human‐Wood Interactions

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

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