“…The 30-mm-wide party balloon inflation provides 20 to 25 mm Hg of positive end-expiratory pressure to the patient’s airway, 3 thereby increasing intrathoracic pressure, decreasing venous return, and enhancing venous return to the RA more effectively than does the conventional VM. Therefore, the PBIM approach may surpass the conventional VM in detecting right-to-left shunts in patients with a PFO.…”