“…While initially deployed under a "compassionate use/expanded access" protocol (1,2), as of December 19, 2019, the vaccine was officially licensed by both the American (Food and Drug Administration, FDA) and European (European Medicines Agency) regulatory agencies (3,4). Wide use of this vaccine was supported by evidence gathered in clinical trials and other studies, including those postlicensure conducted in North America and West Africa, which demonstrated short-term vaccine efficacy (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). In addition to short-term protection, clinical trials and other studies have provided evidence of Ebolavirus Zaire (EBOV)-specific antibody persistence up to 2 y postvaccination, suggesting that the vaccine may continue to offer protective immunity over time (5,7,8,14,15).…”