Particulate matter components, sources, and health: Systematic approaches to testing effects

Adams, Kate; Greenbaum, Daniel S.; Shaikh, Rashid; Erp, Annemoon M. van; Russell, Armistead G.

doi:10.1080/10962247.2014.1001884

Cited by 218 publications

(131 citation statements)

References 47 publications

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“…Particulate matter (PM), a composite of solid particles and liquid droplets suspended in air, is classified into two major categories: coarse particles (PM 10-2.5 ) and fine particles (PM 2.5 ; Hamanaka & Mutlu, 2018). PM is closely linked to CVD, as reflected in a range of illness-relevant biomarkers, including C-reactive protein (CRP) and interleukin-6 (IL-6), involved in systemic inflammation (Adams, Greenbaum, Shaikh, van Erp, & Russell, 2015;Du, Xu, Chu, Guo, & Wang, 2016;Pope et al, 2016;Tsai et al, 2012;Wu, Jin, & Carlsten, 2018). Nascent literature in positive psychology suggests that psychological factors (i.e., subjective well-being and mental health), hold potential to moderate inflammatory responses to environmental air pollutants, providing considerable promise as a future intervention focus (Fredrickson et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women: A research protocol

Brooks

Berry

Currin

et al. 2019

Research in Nursing & Health

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American Indian women are more likely to die from cardiovascular disease (CVD) than White or African American women. Inflammatory processes may underlie CVD disparities by gender and race and may be critical to understanding population‐specific drivers and potential buffers. Exposure to environmental air pollutants, especially particulate matter (PM), is known to be an important catalyst in CVD‐associated inflammation. Positive psychological states, associated with low levels of inflammatory gene expression, could serve to moderate the inflammatory response to environmental air pollutants and ultimately lead to better cardiovascular health outcomes. The aim of the ongoing community‐engaged and NIH‐funded study described in this study protocol is to address the racial and gender gaps in CVD mortality by investigating the contextually relevant and culturally important determinants of health among American Indian women. In this paper we describe the procedures used to examine the relationship between environmental air pollutant exposures (PM10‐2.5 and PM 2.5), psychological factors (e.g., depressive symptoms, posttraumatic stress symptoms, eudemonic well‐being, and positive emotions), and cardiovascular‐associated inflammation (hs‐CRP, IL‐6, Amyloid A, CBCs with differentials) in a sample of 150 women 18–50 years of age from the Lumbee Tribe in southeastern North Carolina. We describe lessons learned and strategies used in developing a community‐engaged approach to enhance recruitment of American Indian women in biomedical research. The empirical data and community infrastructure resulting from this study will be foundational in designing and testing future interventions to reduce CVD‐associated morbidity and mortality in American Indian women.

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Section: Introductionmentioning

confidence: 99%

A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women: A research protocol

Brooks

Berry

Currin

et al. 2019

Research in Nursing & Health

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“…Since the composition of the atmospheric particulate matter (PM) depends on the sources and their chemical transformation in the atmosphere, an important question is which PM constituents are responsible for the adverse human health effects. Sulfate, organic carbon (OC) and transition metals have been shown to be more prominently associated with adverse health outcomes than other pollutants (Lippmann et al, 2013;Adams et al, 2015;Vedal et al, 2013;Burnett et al, 2000), even though there is no toxicological evidence supporting a causal role (WHO, 2013b). It is 50 generally hypothesized that the adverse health effects caused by PM largely derive from oxidative stress induced by reactive oxygen species (ROS).…”

Section: Introductionmentioning

confidence: 99%

Predominance of Secondary Organic Aerosol to Particle-bound Reactive Oxygen Species Activity in Fine Ambient Aerosol

Zhou¹,

Elser²,

Huang³

et al. 2019

Preprint

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<p><strong>Abstract.</strong> Reactive oxygen species (ROS) are believed to contribute to the adverse health effects of aerosols. This may happen by inhaled particle-bound (exogenic) ROS (PB-ROS) or by ROS formed within the respiratory tract by certain aerosol components (endogenic ROS). We investigated the chemical composition of aerosols and their exogenic ROS content at the two contrasting locations Beijing (China) and Bern (Switzerland). We apportioned the ambient organic aerosol to different sources and attributed the observed PB-ROS to them. The oxygenated organic aerosol (OOA, a proxy for secondary organic aerosol, SOA) explained the highest fraction of the exogenic ROS concentration variance at both locations. We also characterized primary and secondary aerosol emissions generated from different biogenic and anthropogenic sources in smog chamber experiments. The exogenic PB-ROS content in the OOA from these emission sources was comparable to that in the ambient measurements. Our results imply that SOA from gaseous precursors of different anthropogenic emission sources is a crucial source of PB-ROS and should be additionally considered in toxicological and epidemiological studies in an adequate way besides primary emissions. The importance of PB-ROS may be connected to the seasonal trends in health effects of PM reported by epidemiological studies, with elevated incidences of adverse effects in warmer seasons, which are accompanied by more intense atmospheric oxidation processes.</p>

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“…Particles between 2.5 and 10 μ m consist of insoluble organic and biological material. However, finer particles (less than 2.5 μ m) derive mainly from combustion and may be either a carbon core with adsorbed hydrocarbons and metals or secondary particles formed from oxides of sulfur and nitrogen (Adams et al, ). PM2.5 and PM10 particles are small enough to penetrate into the thoracic region of the respiratory system.…”

Section: Introduction and Bibliographical Reviewmentioning

confidence: 99%

“…PM is a complex mixture of extremely small particles and liquid droplets that get into the air. Due to their source, particles differ in size and composition (Adams, Greenbaum, Shaikh, van Erp, & Russell, 2015;Hime, Marks, & Cowie, 2018). As particle size determines site of deposition within the respiratory tract, PM is classified according to its diameter.…”

Section: Introduction and Bibliographical Reviewmentioning

confidence: 99%

Monitoring urban environmental pollution by bivariate control charts: New methodology and case study in Santiago, Chile

et al. 2018

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Particulate matter (PM) pollution is a serious environmental problem. Santiago of Chile is one of the most polluted cities in the world in terms of PM2.5 and PM10. Monitoring of environmental risk is useful for detecting and preventing adverse effects on human health in highly polluted cities. In this paper, we propose a methodology for monitoring PM pollution in Santiago based on bivariate quality control charts and an asymmetric distribution. A simulation study is carried out to evaluate performance of the proposed methodology. A case study with PM pollution real‐world data from Santiago is provided, which shows that the methodology is suitable to alert early episodes of extreme air pollution. The results are in agreement with the critical episodes reported with the current model used by the Chilean health authority.

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Particulate matter components, sources, and health: Systematic approaches to testing effects

Cited by 218 publications

References 47 publications

A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women: A research protocol

A community‐engaged approach to investigate cardiovascular‐associated inflammation among American Indian women: A research protocol

Predominance of Secondary Organic Aerosol to Particle-bound Reactive Oxygen Species Activity in Fine Ambient Aerosol

Monitoring urban environmental pollution by bivariate control charts: New methodology and case study in Santiago, Chile

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