Particularities of Acute Myocardial Infarction in Young Adults

Anghel, Larisa; Prisacariu, Cristina; Sascău, Radu Andy; Macovei, Liviu; Cristea, E; Prisacariu, Georgiana; Stătescu, Cristian

doi:10.2478/jce-2019-0005

Cited by 2 publications

(3 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The presence of antiphospholipid antibodies has been reported in COVID-19 patients with arterial thrombosis complications, although the association with antiphospholipid syndrome has not been evidenced [ 57 ]. Moriarty et al suggest that elevated levels of lipoprotein(a)—a validated risk factor for cardiovascular events—might also represent a thrombotic risk factor in COVID-19 patients [ 58 , 59 ].…”

Section: Covid-19—a Trigger For Systemic Thrombosismentioning

confidence: 99%

“…and psychosocial stress factors, induced by the pandemic [ 74 ]. Recent systematic reviews evidenced that the presence of takotsubo cardiomyopathy in COVID-19 patients was associated with high complication rates (54–80%), irrespective of cardiac comorbidities and was more frequent in older female patients [ 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 ].…”

Section: Covid-19—a Trigger For Systemic Thrombosismentioning

confidence: 99%

See 1 more Smart Citation

Imaging Cardiovascular Inflammation in the COVID-19 Era

et al. 2021

View full text Add to dashboard Cite

Cardiac complications are among the most frequent extrapulmonary manifestations of COVID-19 and are associated with high mortality rates. Moreover, positive SARS-CoV-2 patients with underlying cardiovascular disease are more likely to require intensive care and are at higher risk of death. The underlying mechanism for myocardial injury is multifaceted, in which the severe inflammatory response causes myocardial inflammation, coronary plaque destabilization, acute thrombotic events, and ischemia. Cardiac magnetic resonance (CMR) imaging is the non-invasive method of choice for identifying myocardial injury, and it is able to differentiate between underlying causes in various and often challenging clinical scenarios. Multimodal imaging protocols that incorporate CMR and computed tomography provide a complex evaluation for both respiratory and cardiovascular complications of SARS-CoV2 infection. This, in relation to biological evaluation of systemic inflammation, can guide appropriate therapeutic management in every stage of the disease. The use of artificial intelligence can further improve the diagnostic accuracy of these imaging techniques, thus enabling risk stratification and evaluation of prognosis. The present manuscript aims to review the current knowledge on the possible modalities for imaging COVID-related myocardial inflammation or post-COVID coronary inflammation and atherosclerosis.

show abstract

Section: Covid-19—a Trigger For Systemic Thrombosismentioning

confidence: 99%

Section: Covid-19—a Trigger For Systemic Thrombosismentioning

confidence: 99%

Imaging Cardiovascular Inflammation in the COVID-19 Era

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Cyril and Methodius" in Skopje, Vodnjanska Str. 17, 1000 Skopje, Republic of N. Macedonia, e-mail: pejkovh@yahoo.com, mobile: +38978483425 authors believe that these terms should cover the population up to 45 years of age [2,5,6]. Hence, in our research, the previously mentioned terms will refer to persons up to 45 years of age.…”

Section: Introductionmentioning

confidence: 98%

Association of the Polymorphism rs3918242 of the Matrix Metalloproteinase-9 Gene with Coronary Artery Disease in a Younger Population

Boshev

Stankovic

Panov

et al. 2023

Prilozi

View full text Add to dashboard Cite

Coronary artery disease (CAD) is a complex disease resulting from the interaction of numerous so-called traditional risk factors and comorbid conditions on the one side (such as dyslipidemia, smoking, obesity, diabetes, hypertension) and genetic factors on the other. The evidence of a genetic contribution to the development of CAD, especially in the last 2 decades is consistent. It is important that a number of established gene polymorphisms in the younger CAD population are in the genes involved in the inflammatory response and tissue maintenance and remodeling processes. The aim of this study is to investigate the association of the rs3918242 polymorphism of the matrix metal-loproteinase 9 (MMP9) gene with the coronary artery disease in the younger population. In this observational genetic-association study of cases and controls, the demographic, clinical, laboratory and genetic data of the younger population in a group of selected 70 CAD patients aged up to 45 years were analyzed, of which 35 patients have negative and 35 have positive coronary angiography finding, and 43 are men and 27 are women. The analysis of the genotypic and allelic frequency determined an association of the polymorphism and the occurrence of the positive coronary angiographic findings in the population of patients under the age of 45. The carriers of the heterozygous genotype CT have almost 5 times higher probability of having a positive coronary angiography finding compared to the carriers of the reference homozygous genotype CC (p=0.012). Thus, this parameter could be used for clinical risk assessment for the development of CAD.

show abstract

Particularities of Acute Myocardial Infarction in Young Adults

Cited by 2 publications

References 44 publications

Imaging Cardiovascular Inflammation in the COVID-19 Era

Imaging Cardiovascular Inflammation in the COVID-19 Era

Association of the Polymorphism rs3918242 of the Matrix Metalloproteinase-9 Gene with Coronary Artery Disease in a Younger Population

Contact Info

Product

Resources

About