Particularités épidémio-cliniques et thérapeutique des infections urinaires chez les diabétiques

Knani, Habiba; Marrakchi, W.; Kooli, I.; Brahim, H. Ben; Toumi, A.; Aouam, A.; Chakroun, M.

doi:10.1016/j.ando.2020.07.822

Cited by 1 publication

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“…The difference might be due, in part, to the fact that we only took into account UTI leading to hospitalization, whereas for these other authors, it was not specified whether UTI was the main diagnosis. However, it is known that diabetic subjects suffer 4 to 5 times more pyelonephritis than nondiabetics 24 and diabetes increases the risk of hospitalization for pyelonephritis by a factor of 3. 25 Cystitis, which is less severe and does not present systemic symptoms, can be treated on an outpatient basis, which explains why it is less frequent in hospitalization.…”

Section: Discussionmentioning

confidence: 99%

Urinary tract infection in diabetics hospitalized in Befelatanana Hospital, Antananarivo: Epidemiological, clinical, biological profiles and risk factors for multidrug‐resistant bacterial infection

Raherison,

Raharinavalona,

Razanamparany

et al. 2023

Clinical Case Reports

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Key Clinical MessageThe main type of urinary tract infection in hospitalized diabetics in Antananarivo is acute pyelonephritis; Escherichia coli is the most isolated uropathogen; imipenem, amikacin, fosfomycin and ceftriaxone are the major antibiotics for which Escherichia coli retain good sensitivity; Type 2 diabetes is predictive factor for infection by multidrug resistant bacteria.AbstractThis study aimed to describe the epidemiological‐clinical profiles of diabetics hospitalized for bacterial urinary tract infections in the Endocrinology Department of Befelatanana Hospital, to identify the main bacteria responsible, their antibiotic sensitivity profile and the factors associated with multidrug‐resistant bacterial infection. A cross‐sectional study was conducted between March 2017 and March 2020 involving all diabetics hospitalized for documented community‐acquired bacterial urinary tract infection during this period. The hospital prevalence of urinary tract infections was 4.64%. The mean age of the patients was 59.06 ± 14.26 years and the sex ratio was 0.15. The main sign was fever (55.76%). The main clinical form was uncomplicated acute pyelonephritis (38.46%). Fifty‐seven bacterial uropathogens were isolated. The most frequent was Escherichia coli (77.19%). Escherichia coli was sensitive to ertapenem and nitrofurantoin in 100% of cases, to Amikacin in 97.5% of cases, to Fosfomycin in 94.4% of cases and to Ceftriaxone in 80.65% of cases. Thirteen patients were infected with multidrug‐resistant bacteria, all of them are extended‐spectrum beta‐lactamase‐producing Enterobacteriaceae. Only the type of diabetes was associated with multidrug‐resistant bacteria infection. The epidemiological‐clinical and biological characteristics of urinary tract infections in our diabetics are similar to those reported in the literature. Compliance with the rules of proper antibiotic use is imperative to limit the emergence and spread of multidrug‐resistant bacteria.

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Section: Discussionmentioning

confidence: 99%